CAS 113775-47-6
:Dexmedetomidine
Description:
Dexmedetomidine is a selective alpha-2 adrenergic agonist primarily used for its sedative and analgesic properties in clinical settings, particularly in intensive care and during surgical procedures. It is known for its ability to induce sedation without causing significant respiratory depression, making it a preferred choice for patients requiring sedation while maintaining airway reflexes. The compound has a relatively short half-life, allowing for rapid onset and offset of action, which is beneficial for procedures requiring quick recovery. Dexmedetomidine is typically administered intravenously and is characterized by its high lipid solubility, which facilitates its distribution in the central nervous system. Its pharmacological effects include sedation, analgesia, and anxiolysis, with minimal impact on cardiovascular stability. The substance is also noted for its unique mechanism of action, which involves the inhibition of norepinephrine release, leading to decreased sympathetic outflow. Due to its specific properties, dexmedetomidine is often utilized in both adult and pediatric populations, although careful monitoring is essential to manage potential side effects such as hypotension and bradycardia.
Formula:C13H16N2
InChI:InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m0/s1
InChI key:InChIKey=CUHVIMMYOGQXCV-NSHDSACASA-N
SMILES:[C@H](C)(C1=C(C)C(C)=CC=C1)C2=CN=CN2
Synonyms:- (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
- (+)-Medetomidine
- (S)-Medetomidine
- 1H-Imidazole 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-
- 1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-, (R)-
- 1H-Imidazole, 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-
- 1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-, (S)-
- 5-[(1R)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
- 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
- Dexmedetomidina
- Dexmedetomidina [INN-Spanish]
- Dexmedetomidinehclc13H16N2.Hcl
- Dexmedetomidinum
- Dexmedetomidinum [INN-Latin]
- Mpv 1440
- Precedex
- Unii-67Vb76Hono
- d-Medetomidine
- See more synonyms
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Found 10 products.
Dexmedetomidine Hydrochloride
CAS:Formula:C13H16N2·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:236.741H-Imidazole, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-
CAS:Formula:C13H16N2Purity:98%Color and Shape:SolidMolecular weight:200.2795Dexmedetomidine
CAS:Formula:C13H16N2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:200.29Dexmedetomidine
CAS:<p>Dexmedetomidine: a central alpha-2 adrenergic agonist for general anesthesia.</p>Formula:C13H16N2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:200.28Dexmedetomidine
CAS:Controlled Product<p>Applications Dexmedetomidine is an α2-Adrenergic agonist; (+)-isomer of Medetomidine; sedative; analgesic.<br>References Rajala, R., et al.: Eur. J. Pharm. Sci., 1, 219 (1994), Jalonen, J., et al.: Anesthesiology, 86, 331 (1997), Talke, P., et al.: Anesth. Analg., 85, 1136 (1997), Bhana, N., et al.: Drugs, 59, 263 (2000),<br></p>Formula:C13H16N2Color and Shape:NeatMolecular weight:200.28Chloro-Dexmedetomidine
CAS:Controlled ProductFormula:C13H15ClN2Color and Shape:NeatMolecular weight:234.725Dexmedetomidine
CAS:Controlled Product<p>α2-adrenoceptor agonist; analgesic; sedative; anxiolytic</p>Formula:C13H16N2Purity:Min. 95%Molecular weight:200.28 g/mol
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