CAS 1138-80-3

N-Carbobenzyloxyglycine

Description:

N-Carbobenzyloxyglycine, also known as Cbz-Gly, is an amino acid derivative characterized by the presence of a carbobenzyloxy (Cbz) protecting group attached to the amino group of glycine. This compound typically appears as a white to off-white crystalline solid and is soluble in organic solvents such as methanol and dichloromethane, but less soluble in water. The Cbz group serves as a protective moiety, making N-Carbobenzyloxyglycine useful in peptide synthesis, as it can be selectively removed under specific conditions to yield the free amino acid. The compound is often utilized in organic synthesis and medicinal chemistry, particularly in the development of peptide-based drugs. Its molecular structure includes a glycine backbone, which contributes to its role in biological systems, and the Cbz group enhances its stability and reactivity in various chemical reactions. As with many chemical substances, proper handling and safety precautions are essential due to potential hazards associated with its use.

Formula: C₁₀H₁₁NO₄

InChI: InChI=1/C10H11NO4/c12-9(13)6-11-10(14)15-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)/p-1

InChI key: InChIKey=CJUMAFVKTCBCJK-UHFFFAOYSA-N

SMILES: C(OC(NCC(O)=O)=O)C1=CC=CC=C1

Synonyms:

• (Carbobenzoxy)glycine
• (Carbobenzyloxy)glycine
• 2-(Benzyloxycarbonylamino)acetic acid
• 2-(Phenylmethoxycarbonylamino)acetic acid
• Benzyloxycarbonylglycine
• Cbz-Gly-OH
• Cbz-glycine
• Glycine, N-[(phenylmethoxy)carbonyl]-
• Glycine, N-carboxy-, N-benzyl ester
• N-(Benzyloxycarbonyl)glycine
• N-(Carbobenzoxy)glycine
• N-(Carbobenzyloxy)glycine
• N-(α-Carbobenzoxy)glycine
• N-Benzyloxycarbonylglycin
• N-Benzyloxycarbonylglycine
• N-CBZ-Glycine N-Carbobenzyloxy-glycine
• N-Carboxyglycine N-benzyl ester
• N-Cbz-Gly-OH
• N-Cbz-glycine
• N-[(Phenylmethoxy)carbonyl]glycine
• N-[(benzyloxy)carbonyl]glycine{[(benzyloxy)carbonyl]amino}acetate
• N-benciloxicarbonilglicina
• N-cbz-glycine crystalline
• N^α-(Benzyloxycarbonyl)glycine
• Nsc 2526
• Nα-(Benzyloxycarbonyl)glycine
• Z-Gly-OH
• Z-glycine
• [[(Benzyloxy)carbonyl]amino]acetic acid
• z-Gly
• RARECHEM AL BO 0395
• N-CARBOBENZOXYGLYCINE
• Z-L-GLYCINE
• CBZ-GLY
• CARBOBENZYLOXYGLYCINE
• N-ALPHA-BENZYLOXYCARBONYL-GLYCINE
• N-CBZ-GLYCINE-OH
• N-ALPHA-CBZ-GLYCINE
• N-ALPHA-CARBOBENZOXY-GLYCINE
• 2-([(BENZYLOXY)CARBONYL]AMINO)ACETIC ACID
• LABOTEST-BB LT00005891
• BENZYLOXYCARBONYL-GLYCINE
• TIMTEC-BB SBB003458

N-Carbobenzoxyglycine

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 209.20

Ref: 3B-C0575

N-Benzyloxycarbonylglycine, 98+%

CAS: 1138-80-3

N-Carbobenzoxyglycine is used in the dipeptide synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has n

Formula: C₁₀H₁₁NO₄

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 209.20

Ref: 02-A15928

Z-Gly-OH

CAS: 1138-80-3

Bachem ID: 4000228.

Formula: C₁₀H₁₁NO₄

Purity: 98.8%

Color and Shape: White

Molecular weight: 209.2

Ref: 01-4000228

Glycine, N-[(phenylmethoxy)carbonyl]-

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 209.1986

Ref: IN-DA0009QA

Z-Gly-OH

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Molecular weight: 209.20

Ref: 7W-GM7548

Z-Glycine

CAS: 1138-80-3

Z-Glycine

Purity: ≥98%

Molecular weight: 209.2g/mol

Ref: 54-BUP19004

Z-Glycine

CAS: 1138-80-3

N-Benzyloxycarbonylglycine is a lipid-like drug designed for enhanced brain penetration.

Formula: C₁₀H₁₁NO₄

Purity: 99.88%

Color and Shape: Slightly Beige Powder

Molecular weight: 209.2

Ref: TM-T33604

Z-Glycine

CAS: 1138-80-3

Z-Glycine

Purity: 98%

Molecular weight: 209.20g/mol

Ref: 54-BIZ0428

N-Carbobenzoxyglycine

CAS: 1138-80-3

Applications N-Carbobenzoxyglycine is used in the dipeptide synthesis.
References Hans, D., et al.: Med. Chem., 2, 627 (2006), Guzman, F., et al.: J. Biotechnol., 10, 279 (2007), Vlieghe, P., et al.: Drug Discov. Today, 15, 40 (2010),

Formula: C₁₀H₁₁NO₄

Color and Shape: Neat

Molecular weight: 209.2

Ref: TR-C175995

Cbz-glycine

CAS: 1138-80-3

Cbz-glycine is a hydrogen bond donor that can react with trifluoroacetic acid in a one-step reaction to form an ester hydrochloride. It is used in the synthesis of monoclonal antibodies and has been shown to inhibit the growth of receptor cells. Cbz-glycine reacts with protocatechuic acid, pyrazinoic acid, and ester hydrochloride to form pharmacokinetic properties. It has been shown to have pharmacokinetic properties by inhibiting prostaglandin synthesis.

Formula: C₁₀H₁₁NO₄

Purity: Min. 95%

Molecular weight: 209.2 g/mol

Ref: 3D-FC39362

Z-Gly-OH

CAS: 1138-80-3

M03051 - Z-Gly-OH

Formula: C₁₀H₁₁NO₄

Purity: 95%

Color and Shape: Solid, White to off-white crystalline powder

Molecular weight: 209.201

Ref: 10-M03051

Z-Glycine extrapure, 99%

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Purity: min. 99 %

Color and Shape: White, Crystalline powder

Molecular weight: 209.2

Ref: SR-86632

N-Carbobenzoxyglycine

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Molecular weight: 209.2

Ref: ST-EA-CP-E12036