CAS 113805-71-3

Olopatadine Methyl Ester

Description:

Olopatadine Methyl Ester, identified by the CAS number 113805-71-3, is a chemical compound derived from olopatadine, which is primarily known for its use as an antihistamine in the treatment of allergic conditions. This compound exhibits properties typical of antihistamines, including the ability to inhibit the release of histamine from mast cells, thereby alleviating allergic symptoms. It is characterized by its relatively low molecular weight and specific functional groups that contribute to its pharmacological activity. The methyl ester form may enhance lipophilicity, potentially improving its absorption and bioavailability. In terms of solubility, olopatadine derivatives generally exhibit moderate solubility in organic solvents, while their solubility in water can vary. The compound's stability, reactivity, and interaction with biological systems are influenced by its chemical structure, making it a subject of interest in pharmaceutical research. Overall, Olopatadine Methyl Ester represents a modification of the parent compound aimed at optimizing therapeutic efficacy in allergy management.

Formula: C₂₁H₂₃NO₃

Synonyms:

• Olopatadine Methyl ester Hydrochloride
• Olopatadine Impurity 11
• (Z)-11-&lt
• Olopatadine Methyl Ester
• -6,11-dihydrodibenz
• oxepin-2-carboxylic acid methyl ester
• (Z)-11-<3-(dimethylamino)propylidene>-6,11-dihydrodibenz
• (11Z)-11-[3-(DiMethylaMino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-carboxylic Acid Methyl Ester
• Dibenz[b,e]oxepin-2-carboxylic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, methyl ester, (11Z)-
• 3-(dimethylamino)propylidene&gt

Olopatadine Methyl Ester

Controlled Product

CAS: 113805-71-3

Applications Olopatadine (O575000) derivative, a histamine H1-receptor antagonist and mast cell stabilizer. Antiallergic; antihistaminic.
References Kamei, C., et al.: Arzneim.-Forsch., 45, 1005 (1995), Sharif, N.A., et al.: J. Pharmacol. Exp. Ther., 278, 1252 (1996), Abelson, M.B., et al.: Am. J. Ophthalmol., 125, 797 (1998),

Formula: C₂₁H₂₃NO₃

Color and Shape: Neat

Molecular weight: 337.41

Ref: TR-O575015

Olopatadine methyl ester

CAS: 113805-71-3

Olopatadine methyl ester is a non-sedating antihistamine that is used to treat allergic symptoms. It has a rapid onset of action and is effective for 24 hours. Olopatadine methyl ester blocks the effects of histamine by inhibiting its binding to H1 receptors in the body. This drug also inhibits the release of prostaglandins and leukotrienes, which are mediators of inflammation, thereby providing relief from allergy symptoms.

Formula: C₂₁H₂₃NO₃

Purity: Min. 95%

Molecular weight: 337.4 g/mol

Ref: 3D-NEA80571