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CAS 113806-05-6

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Olopatadine

Description:
Olopatadine is a selective antihistamine primarily used in the treatment of allergic conjunctivitis and allergic rhinitis. It functions as a dual-action agent, exhibiting both antihistaminic and mast cell stabilizing properties, which help alleviate symptoms such as itching, redness, and inflammation associated with allergic reactions. Chemically, olopatadine is classified as a piperidine derivative and has a molecular formula that reflects its complex structure, which includes multiple functional groups that contribute to its pharmacological activity. The substance is typically administered as an ophthalmic solution or nasal spray, allowing for localized treatment with minimal systemic absorption. Olopatadine is known for its relatively low sedative effects compared to first-generation antihistamines, making it a preferred choice for patients requiring long-term management of allergy symptoms. Its safety profile is well-established, with common side effects being mild and transient. Overall, olopatadine represents an effective therapeutic option for managing allergic conditions, enhancing patient comfort and quality of life.
Formula:C21H23NO3
InChI:InChI=1S/C21H23NO3/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24)/b18-8-
InChI key:InChIKey=JBIMVDZLSHOPLA-LSCVHKIXSA-N
SMILES:C(\CCN(C)C)=C/1\C=2C(OCC=3C1=CC=CC3)=CC=C(CC(O)=O)C2
Synonyms:
  • Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (Z)-
  • (11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid
  • Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-
  • Olopatadine
  • 11-[(Z)-3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid
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