CAS 113826-06-5

(R)-Glycidyl tosylate

Description:

(R)-Glycidyl tosylate is an organic compound characterized by its epoxide functional group and tosylate moiety, which contributes to its reactivity and utility in organic synthesis. It is typically a colorless to pale yellow liquid, exhibiting a relatively low viscosity. The compound is known for its chiral nature, as indicated by the (R) configuration, which can influence its reactivity and interactions in asymmetric synthesis. Its structure includes a three-membered epoxide ring, making it a valuable intermediate in the preparation of various biologically active compounds and pharmaceuticals. The tosylate group enhances its electrophilicity, facilitating nucleophilic attack in reactions such as ring-opening or substitution. (R)-Glycidyl tosylate is soluble in common organic solvents, which aids in its application in laboratory settings. Safety considerations should be taken into account, as it may be irritant and potentially hazardous upon exposure. Overall, its unique structural features and reactivity profile make it a significant compound in synthetic organic chemistry.

Formula: C₁₀H₁₂O₄S

InChI: InChI=1S/C10H12O4S/c1-8-2-4-10(5-3-8)15(11,12)14-7-9-6-13-9/h2-5,9H,6-7H2,1H3/t9-/m1/s1

InChI key: InChIKey=NOQXXYIGRPAZJC-SECBINFHSA-N

SMILES: S(OC[C@H]1CO1)(=O)(=O)C2=CC=C(C)C=C2

Synonyms:

• (-)-Glycidyl tosylate
• (2R)-(-)-Glycidyl Tosylate
• (2R)-oxiran-2-ylmethyl 4-methylbenzenesulfonate
• (2S)-oxiran-2-ylmethyl 4-methylbenzenesulfonate
• (R)-(-)-Glycidyl p-toluenesulfonate
• (R)-(-)-Glycidyl tosylate
• (R)-(-)-Oxiran-2-ylmethyl 4-methylbenzenesulfonate
• (R)-Glycidol tosylate
• (R)-GlycidylTosylate
• (R)-Oxiran-2-ylmethyl toluene-4-sulfonate
• (R)-Oxiran-2-ylmethyl tosylate
• (S)-Oxiranemethanol 4-Methylbenzenesulfonate
• 2-Oxiranemethanol, 2-(4-methylbenzenesulfonate), (2R)-
• 4-Methylbenzyl (2R)-oxiran-2-ylmethanesulfonate
• Oxiranemethanol, 4-methylbenzenesulfonate, (2R)-
• Oxiranemethanol, 4-methylbenzenesulfonate, (R)-
• [(2R)-Oxiran-2-yl]methyl 4-methylbenzene-1-sulfonate

2-Oxiranemethanol, 2-(4-methylbenzenesulfonate), (2R)-

CAS: 113826-06-5

Formula: C₁₀H₁₂O₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 228.2649

Ref: IN-DA0009TL

(2R)-(-)-Glycidyl tosylate

CAS: 113826-06-5

(2R)-(-)-Glycidyl tosylate

Purity: 98%,98%ee

Molecular weight: 228.27g/mol

Ref: 54-BIG1004

(2R)-(-)-Glycidyl p-Toluenesulfonate

CAS: 113826-06-5

Formula: C₁₀H₁₂O₄S

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 228.26

Ref: 3B-T1611

(S)-Glycidyl Tosylate

CAS: 113826-06-5

Formula: C₁₀H₁₂O₄S

Molecular weight: 228.26

Ref: 4Z-S-226

(2R)-Oxiran-2-ylmethyl 4-methylbenzenesulfonate

CAS: 113826-06-5

Formula: C₁₀H₁₂O₄S

Purity: 97%

Color and Shape: White crystalline

Molecular weight: 228.26

Ref: 10-F069063

(2R)-(-)-Glycidyl tosylate

CAS: 113826-06-5

(2R)-(-)-Glycidyl tosylate is a chiral epoxide that can be prepared through an asymmetric synthesis. It has been used in the synthesis of a series of chiral epoxides, which exhibit potent inhibitory activity against receptor activity. In addition, (2R)-(-)-glycidyl tosylate is a nucleophilic cross-linking agent that forms covalent bonds with proteins. It also reacts with hydroxyl groups and tiglic acid to form reaction intermediates, which are useful in the synthesis of pharmaceuticals.

Formula: C₁₀H₁₂O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 228.27 g/mol

Ref: 3D-FG23688

(2R)-(-)-Glycidyl Tosylate

Controlled Product

CAS: 113826-06-5

Applications Protected Glycidol, used as an intermediate in the preparation of neurochemicals.
References Qian, L., et al.: ChemMedChem., 1, 376 (2006), Shimizu, K., et al.: Bioorg. Med. Chem., 14, 1838 (2006), Pedersen, P., et al.: J. Med. Chem., 52, 3408 (2009),

Formula: C₁₀H₁₂O₄S

Color and Shape: Neat

Molecular weight: 228.26

Ref: TR-G616000

(S)-Glycidyl Tosylate

CAS: 113826-06-5

Formula: C₁₀H₁₂O₄S

Molecular weight: 228.26

Ref: ST-EA-CP-S49013