CAS 113886-70-7

2'-(O-METHYL)-5-METHYLCYTIDINE

Description:

2'-(O-Methyl)-5-methylcytidine is a modified nucleoside that features a methyl group at the 5-position of the cytidine base and a methoxy group at the 2' position of the ribose sugar. This compound is characterized by its structural modifications that enhance its stability and influence its biological activity, particularly in the context of RNA. The presence of the O-methyl group can improve resistance to enzymatic degradation, making it of interest in therapeutic applications, such as in the development of antiviral agents or in RNA-based therapeutics. Additionally, the methylation at the 5-position can affect the nucleoside's interaction with RNA polymerases and other proteins, potentially altering its role in cellular processes. The compound is typically studied in biochemical and pharmacological contexts, where its unique properties may contribute to the understanding of nucleic acid function and regulation. Its CAS number, 113886-70-7, is a unique identifier that facilitates its identification in chemical databases and literature.

Formula: C₁₁H₁₇N₃O₅

Synonyms:

• 5-Methyl-2'-O-Methylcytidine
• 2'-O-Methyl-5-methyl-D-cytidine

Cytidine, 5-methyl-2'-O-methyl-

CAS: 113886-70-7

Formula: C₁₁H₁₇N₃O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 271.2698

Ref: IN-DA0009ZJ

5-Methyl-2′-O-methylcytidine

CAS: 113886-70-7

5-Methyl-2′-O-methylcytidine

Purity: 98%

Ref: 54-OR1039974

2''-O-Methyl-5-methylcytidine

CAS: 113886-70-7

Ref: 7W-GN7318

2'-O-Methyl-5-methylcytidine

CAS: 113886-70-7

2'-O-Methyl-5-methylcytidine is a 2'-O-Methyl nucleoside.

Formula: C₁₁H₁₇N₃O₅

Color and Shape: Solid

Molecular weight: 271.27

Ref: TM-TNU0124

2'-O-Methyl-5-methylcytidine

CAS: 113886-70-7

2'-O-Methyl-5-methylcytidine is a nucleoside that is categorized as a modified nucleic acid. It is structurally similar to cytidine, but has an additional methyl group. 2'-O-Methyl-5-methylcytidine stabilizes the conformational structure of nucleic acids and can be used to regulate the activity of enzymes. This modified nucleoside has been shown to have thermophilic characteristics when it interacts with human cells. The stability of 2'-O-Methyl-5-methylcytidine increases with increasing temperature, making it possible for this molecule to regulate gene expression in organisms that live at high temperatures.

Formula: C₁₁H₁₇N₃O₅

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 271.27 g/mol

Ref: 3D-NM06424

5-METHYL-2′-O-METHYLCYTIDINE

CAS: 113886-70-7

Formula: C₁₁H₁₇N₃O₅

Purity: 95.0%

Molecular weight: 271.117

Ref: 10-F527876

5-Methyl-2'-O-methylcytidine

CAS: 113886-70-7

Applications 5-Methyl-2’-O-methylcytidine is found in tRNAs from extremely thermophilic archaebacteria. Also, it destabilizes the triplex formation with double-stranded DNA.
References Kawai, G., et al.: Nucleic Acids Symp., 25, 49-50 (1991); Shimizu, M., et al.: Bioorg. Med. Chem. Lett., 4, 1029-1032 (1994)

Formula: C₁₁H₁₇N₃O₅

Color and Shape: Neat

Molecular weight: 271.270

Ref: TR-M263410