CAS 113886-71-8: N4-Acetyl-2′-O-methylcytidine

Description: N4-Acetyl-2′-O-methylcytidine is a modified nucleoside that features an acetyl group at the N4 position of the cytidine base and a methoxy group at the 2′ position of the ribose sugar. This compound is characterized by its structural modifications that enhance its stability and bioavailability compared to unmodified nucleosides. The acetyl group can influence the nucleoside's interaction with enzymes and its incorporation into RNA, potentially affecting its biological activity. The 2′-O-methyl modification is known to confer resistance to ribonucleases, making it a valuable component in therapeutic applications, particularly in the development of RNA-based drugs and vaccines. N4-Acetyl-2′-O-methylcytidine is often studied in the context of RNA synthesis and modification, as well as in the design of oligonucleotides for research and therapeutic purposes. Its unique properties make it a subject of interest in molecular biology and medicinal chemistry, where it may play a role in enhancing the efficacy of RNA therapeutics.

Formula: C₁₂H₁₇N₃O₆

InChI: InChI=1S/C12H17N3O6/c1-6(17)13-8-3-4-15(12(19)14-8)11-10(20-2)9(18)7(5-16)21-11/h3-4,7,9-11,16,18H,5H2,1-2H3,(H,13,14,17,19)/t7-,9-,10-,11-/m1/s1

InChI key: InChIKey=CYDFBLGNJUNSCC-QCNRFFRDSA-N

SMILES: O=C1N=C(C=CN1C2OC(CO)C(O)C2OC)NC(=O)C

Synonyms:

• N-Acetyl-2'-O-methylcytidine
• N4-Acetyl-2'-O-Methyl-cytidine
• N4-Acetyl-2'-O-methylcytidine
• N⁴-Acetyl-2′-O-methylcytidine
• Cytidine, N-acetyl-2′-O-methyl-
• N4-Ac-2'-OMe-rC

Cytidine, N-acetyl-2'-O-methyl-

CAS: 113886-71-8

• Formula: C₁₂H₁₇N₃O₆
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 299.2799

N4-Acetyl-2''-O-methylcytidine

CAS: 113886-71-8

• Formula: C₁₂H₁₇N₃O₆
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 299.28

N4-ACETYL-2'-O-METHYL-CYTIDINE

CAS: 113886-71-8

• Purity: 95.0%
• Color and Shape: Liquid
• Molecular weight: 299.2829895019531

N4-Acetyl-2'-O-methylcytidine

CAS: 113886-71-8

N4-Acetyl-2'-O-methylcytidine is a chemical compound that is an analog of cytidine. It has been shown …

• Formula: C₁₂H₁₇N₃O₆
• Purity: Min. 95%
• Color and Shape: White Off-White Powder
• Molecular weight: 299.29 g/mol

N4-Acetyl-2’-O-methyl-cytidine

CAS: 113886-71-8

Applications N4-Acetyl-2’-O-methyl-cytidine is a useful compound in the synthesis of functionalized oligonucleotides. References Jezowska, M., …

• Formula: C₁₂H₁₇N₃O₆
• Color and Shape: Neat
• Molecular weight: 299.29