CAS 113932-41-5: Tematropium

Description:Tematropium is a synthetic quaternary ammonium compound primarily used as a bronchodilator in the treatment of respiratory conditions such as chronic obstructive pulmonary disease (COPD) and asthma. It functions as an anticholinergic agent, inhibiting the action of acetylcholine on muscarinic receptors in the airways, leading to relaxation of bronchial smooth muscle and improved airflow. Tematropium is characterized by its relatively long duration of action, which allows for once-daily dosing. The compound is typically administered via inhalation, ensuring targeted delivery to the lungs while minimizing systemic side effects. Its chemical structure includes a tropane ring, contributing to its pharmacological properties. As with other anticholinergics, potential side effects may include dry mouth, constipation, and urinary retention, particularly in sensitive populations. Overall, Tematropium represents a valuable therapeutic option in managing obstructive airway diseases, enhancing patient quality of life through improved respiratory function.

Formula:C₂₁H₃₁NO₈S

InChI:InChI=1/C20H28NO4.CH4O4S/c1-4-24-19(22)18(14-8-6-5-7-9-14)20(23)25-17-12-15-10-11-16(13-17)21(15,2)3;1-5-6(2,3)4/h5-9,15-18H,4,10-13H2,1-3H3;1H3,(H,2,3,4)/q+1;/p-1

Synonyms:
Tematropium methylsulfate [USAN]
3alpha-Hydroxy-8-methyl-1alphaH,5alphaH-tropanium methyl sulfate (salt), (+-)-ethyl hydrogen phenylmalonate
8-Azoniabicyclo(3.2.1)octane, 3-(3-ethoxy-1,3-dioxo-2-phenylpropoxy)-8,8-dimethyl-, endo-(+-)-, methyl sulfate
Tematropium methylsulfate
Unii-2T52M232D8
3-[(3-Ethoxy-3-Oxo-2-Phenylpropanoyl)Oxy]-8,8-Dimethyl-8-Azoniabicyclo[3.2.1]Octane Methyl Sulfate

Found 3 products.

Product data	Purity	Price range	Estimated delivery
Tematropium REF: 54-BUP02422CAS: 113932-41-5	≥98%	1,258.00 €~2,289.00 €	Mon 05 May 25
Tematropium methylsulfate REF: 3D-NEA93241CAS: 113932-41-5	Min. 95%	1,778.00 €	Tue 17 Jun 25
Tematropium REF: TM-T10732CAS: 113932-41-5	98.87%	212.00 €~1,691.00 €	Tue 08 Jul 25