CAS 113963-68-1: Bisindolylmaleimide V

Description: Bisindolylmaleimide V is a synthetic compound that belongs to the class of indole derivatives and is primarily recognized for its role as a selective inhibitor of protein kinase C (PKC). This compound features a bisindolyl structure, which contributes to its biological activity, and a maleimide moiety that enhances its binding affinity to target proteins. Characteristically, Bisindolylmaleimide V exhibits a high degree of specificity towards certain PKC isoforms, making it a valuable tool in biochemical research and drug development. It is often utilized in studies related to cell signaling, cancer research, and neurobiology due to its ability to modulate various cellular processes. The compound is typically characterized by its solid state at room temperature and is soluble in organic solvents. Its pharmacological properties, including its potency and selectivity, make it a subject of interest in the development of therapeutic agents aimed at diseases where PKC plays a critical role. Safety and handling precautions are advised, as with many chemical substances, due to potential toxicity.

Formula: C₂₁H₁₅N₃O₂

InChI: InChI=1S/C21H15N3O2/c1-24-20(25)18(14-10-22-16-8-4-2-6-12(14)16)19(21(24)26)15-11-23-17-9-5-3-7-13(15)17/h2-11,22-23H,1H3

InChI key: InChIKey=SWAWYMIKGOHZMR-UHFFFAOYSA-N

SMILES: O=C1C(C2=CNC=3C=CC=CC32)=C(C(=O)N1C)C4=CNC=5C=CC=CC54

Synonyms:

• 1-Methyl-3,4-bis(indol-3-yl)maleimide
• 1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-1-methyl-
• 3,4-Bis(1H-indol-3-yl)-1-methylpyrrole-2,5-dione
• 3,4-di(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione
• Bisindolylmaleimide V
• Methylarcyriarubin
• Methylarcyriarubin A
• N-Methyl-3,4-bis(indol-3-yl)maleimide
• N-Methylbis(indol-3-yl)maleimide
• Ro 31-6045

1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-1-methyl-

CAS: 113963-68-1

• Formula: C₂₁H₁₅N₃O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 341.36269999999996

Bisindolylmaleimide V

CAS: 113963-68-1

• Purity: 90%
• Molecular weight: 341.36g/mol

3,4-Di(1H-Indol-3-Yl)-1-Methyl-1H-Pyrrole-2,5-Dione

CAS: 113963-68-1

• Purity: 98%
• Molecular weight: 341.36g/mol

Bisindolylmaleimide V

CAS: 113963-68-1

• Formula: C₂₁H₁₅N₃O₂
• Purity: >97.0%(HPLC)
• Color and Shape: Light yellow to Brown powder to crystal
• Molecular weight: 341.37

1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-1-methyl-

CAS: 113963-68-1

• Purity: 98%
• Molecular weight: 341.37

Bisindolylmaleimide V

CAS: 113963-68-1

• Formula: C₂₁H₁₅N₃O₂
• Molecular weight: 341.4

Bisindolylmaleimide V

CAS: 113963-68-1

Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.

• Formula: C₂₁H₁₅N₃O₂
• Purity: 90%
• Color and Shape: Red Solid
• Molecular weight: 341.36

1-Methyl-3,4-bis(3-indolyl)maleimide

CAS: 113963-68-1

1-Methyl-3,4-bis(3-indolyl)maleimide (1M3BM) is a chemical compound that has been shown to be an inhibitor of …

• Formula: C₂₁H₁₅N₃O₂
• Purity: Min. 95%
• Molecular weight: 341.36 g/mol