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CAS 113963-68-1

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Bisindolylmaleimide V

Description:
Bisindolylmaleimide V is a synthetic compound that belongs to the class of indole derivatives and is primarily recognized for its role as a selective inhibitor of protein kinase C (PKC). This compound features a bisindolyl structure, which contributes to its biological activity, and a maleimide moiety that enhances its binding affinity to target proteins. Characteristically, Bisindolylmaleimide V exhibits a high degree of specificity towards certain PKC isoforms, making it a valuable tool in biochemical research and drug development. It is often utilized in studies related to cell signaling, cancer research, and neurobiology due to its ability to modulate various cellular processes. The compound is typically characterized by its solid state at room temperature and is soluble in organic solvents. Its pharmacological properties, including its potency and selectivity, make it a subject of interest in the development of therapeutic agents aimed at diseases where PKC plays a critical role. Safety and handling precautions are advised, as with many chemical substances, due to potential toxicity.
Formula:C21H17N3O2
InChI:InChI=1/C21H15N3O2/c1-24-20(25)18(14-10-22-16-8-4-2-6-12(14)16)19(21(24)26)15-11-23-17-9-5-3-7-13(15)17/h2-11,22-23H,1H3
InChI key:InChIKey=SWAWYMIKGOHZMR-UHFFFAOYSA-N
SMILES:O=C1C(=C(C(=O)N1C)C=2C=3C(NC2)=CC=CC3)C=4C=5C(NC4)=CC=CC5
Synonyms:
  • 1-Methyl-3,4-bis(indol-3-yl)maleimide
  • 1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-1-methyl-
  • 3,4-Bis(1H-indol-3-yl)-1-methylpyrrole-2,5-dione
  • 3,4-di(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione
  • Bisindolylmaleimide V
  • Methylarcyriarubin
  • Methylarcyriarubin A
  • N-Methyl-3,4-bis(indol-3-yl)maleimide
  • N-Methylbis(indol-3-yl)maleimide
  • Ro 31-6045
  • See more synonyms
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