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CAS 113994-41-5

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Dehydro Amlodipine (Amlodipine Impurity D)

Description:
Dehydro Amlodipine, also known as Amlodipine Impurity D, is a chemical compound associated with the pharmaceutical drug amlodipine, which is primarily used as an antihypertensive agent. This substance is characterized by its structural modification, specifically the absence of a hydrogen atom at a particular position in the amlodipine molecule, resulting in a dehydrogenated form. It typically appears as a white to off-white solid and is soluble in organic solvents. The compound is of interest in pharmaceutical quality control, as it can be a byproduct of the synthesis of amlodipine and may affect the purity and efficacy of the final product. Its presence is monitored to ensure compliance with regulatory standards. The molecular structure of Dehydro Amlodipine includes a dihydropyridine ring, which is crucial for its biological activity. As an impurity, it is essential to evaluate its potential pharmacological effects and toxicity, although it is generally considered to have lower activity compared to the parent compound.
Formula:C20H23ClN2O5
Synonyms:
  • 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
  • 3-Ethyl 5-Methyl Ester 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate
  • Amlodipine Impurity D
  • 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester Oxalate
  • Dehydro Amlodipine Oxalate
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