CAS 114-33-0
:N′-Methylnicotinamide
Description:
N′-Methylnicotinamide is an organic compound that belongs to the class of nicotinamide derivatives. It is characterized by the presence of a methyl group attached to the nitrogen atom of the nicotinamide structure, which is derived from niacin (vitamin B3). This compound is typically a white to off-white crystalline solid and is soluble in water and various organic solvents, making it versatile for different applications. N′-Methylnicotinamide is known for its role in biological systems, particularly in cellular metabolism and as a potential modulator of certain enzymatic activities. It has been studied for its pharmacological properties, including anti-inflammatory and neuroprotective effects. The compound's molecular structure includes a pyridine ring, which contributes to its chemical reactivity and interaction with biological targets. Due to its properties, N′-Methylnicotinamide is of interest in medicinal chemistry and may have implications in therapeutic applications, although further research is needed to fully elucidate its mechanisms of action and potential benefits.
Formula:C7H8N2O
InChI:InChI=1/C7H8N2O/c1-8-7(10)6-3-2-4-9-5-6/h2-5H,1H3,(H,8,10)
InChI key:InChIKey=ZYVXHFWBYUDDBM-UHFFFAOYSA-N
SMILES:C(NC)(=O)C=1C=CC=NC1
Synonyms:- 3-(Methylcarbamoyl)pyridine
- 3-(N-Methylcarbamoyl)pyridine
- 3-Pyridinecarboxamide, N-methyl-
- Methylnicotinamide
- N-Methyl-3-pyridinecarboxamide
- N-methylpyridine-3-carboxamide
- NSC 66521
- Nicotinamide, N-methyl-
- Nicotinic acid methylamide
- Sr 4415
- METHYLNICOTINAMIDE, N-
- N-METHYLNICOTINAMIDE
- N'-METHYLNICOTINAMIDE
- 3-Pyridinecarboxamide,N-methyl-(9CI)
- See more synonyms
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Found 12 products.
N-Methylnicotinamide
CAS:Formula:C7H8N2OPurity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:136.153-Pyridinecarboxamide, N-methyl-
CAS:Formula:C7H8N2OPurity:96%Color and Shape:SolidMolecular weight:136.1512N-Methylnicotinamide-2,4,5,6-d4
CAS:Purity:99 atom % DColor and Shape:White To Off-White SolidMolecular weight:140.18N-Methylnicotinamide
CAS:<p>N-Methylnicotinamide, a niacin metabolite, is found in urine and indicates niacin levels; high in liver cirrhosis, also a microbial product.</p>Formula:C7H8N2OPurity:99.44%Color and Shape:SolidMolecular weight:136.15N-Methylnicotinamide
CAS:<p>Applications N-Methylnicotinamide is a metabolite of Nicotinamide (N407750), which is a water-soluble vitamin B, incorporated within nicotinamide cofactors such as NADH and NADPH. N-Methylnicotinamide is commonly found in the human urine and is used as a biomarker to study diseases such as liver cirrhosis and type 2 diabetes.<br>References Pumpo, R., et al.: Am. J. Gastroenterol., 96, 1183 (2001); Sharma, M., et al.: J. Chem. Pharm. Res., 2, 416 (2010); Al-Nadaf, A., et al.: Bioorg. Medi. Chem., 18, 3088 (2010); Connor, S., et al.: Mol. Biosyst., 6, 909 (2010);<br></p>Formula:C7H8N2OColor and Shape:NeatMolecular weight:136.15N-Methylnicotinamide
CAS:<p>N-Methylnicotinamide is an experimental drug that is being studied for its ability to treat metabolic disorders, such as fatty-acid oxidation defects. N-Methylnicotinamide is a competitive inhibitor of the enzyme creatine kinase, which is involved in the metabolism of carbohydrates and fats. It has been shown to be effective in vivo in animals as well as in vitro in cell cultures. The compound binds to the active site of creatine kinase, preventing ATP from binding and inhibiting the phosphorylation of ADP. N-Methylnicotinamide has been shown to be effective against animal models of metabolic disorders, including urea cycle disorders and fatty acid oxidation defects. This agent also shows promise for treating human diseases caused by disturbances in mitochondrial function.</p>Purity:Min. 95%
