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CAS 114-49-8

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Scopolamine hydrobromide

Description:
Scopolamine hydrobromide is a tropane alkaloid derived from plants of the Solanaceae family, particularly from the belladonna plant. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. The substance acts primarily as an anticholinergic agent, blocking the action of acetylcholine in the nervous system, which makes it effective in treating motion sickness, nausea, and vomiting. Scopolamine hydrobromide is also used in preoperative settings to reduce salivation and secretions. Its pharmacological effects include sedation, amnesia, and muscle relaxation, but it can also cause side effects such as dry mouth, blurred vision, and drowsiness. Due to its potential for abuse and the risk of severe side effects, its use is carefully monitored in clinical settings. As with any medication, it is essential to use scopolamine hydrobromide under the guidance of a healthcare professional to ensure safety and efficacy.
Formula:C17H22BrNO4
InChI:InChI=1/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13+,14?,15-,16?;/m1./s1
InChI key:InChIKey=WTGQALLALWYDJH-MOUKNHLCSA-N
SMILES:CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].Br
Synonyms:
  • (-)-Scopolamine bromide
  • (-)-Scopolamine, HBr
  • (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl 3-hydroxy-2-phenylpropanoate hydrobromide (1:1)
  • 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
  • 3-Oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]nonane, benzeneacetic acid deriv.
  • 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrobromide (1:1)
  • 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrochloride
  • Beldavrin
  • Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide (1:1), (αS)-
  • Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide, (αS)-
  • See more synonyms
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Found 8 products.
  • Scopolamine HBr (Hyoscine HBr)

    CAS:
    Formula:C17H21NO4·HBr
    Color and Shape:White To Off-White Solid
    Molecular weight:303.36 80.91

    Ref: 4Z-S-012

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Scopolamine hydrobromide

    CAS:
    Formula:C17H22BrNO4
    Purity:95%~99%
    Molecular weight:384.27

    Ref: BP-BP1274

    20mg
    32.00€
    100mg
    48.00€
    1000mg
    103.00€
  • Scopolamine Hydrobromide Trihydrate

    CAS:
    Formula:C17H21NO4·HBr·3H2O
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:438.32

    Ref: 3B-S0021

    1g
    84.00€
    10g
    602.00€
  • (1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide

    CAS:
    <p>(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide</p>
    Purity:≥95%
    Molecular weight:438.31g/mol

    Ref: 54-OR310495

    ne
    To inquire
  • Scopolamine hydrobromide

    CAS:
    Natural alkaloid
    Formula:C17H21NO4HBr
    Purity:≥ 95.0 % (HPLC)
    Color and Shape:Powder
    Molecular weight:384.27

    Ref: 5G-80046

    50mg
    185.00€
    250mg
    678.00€
    500mg
    1,233.00€
    1000mg
    2,312.00€
  • Scopolamine Hydrobromide Hydrate

    Controlled Product
    CAS:
    <p>Applications Scopolamine Hydrobromide Hydrate is an acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Neuroprotective &amp; Neuroresearch Product.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brand, J.J., et al.: Lancet, 2, 232 (1970); Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979); Clissold, S.P., et al.: Drugs, 29, 189 (1985); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990);<br></p>
    Formula:C17H21NO4·HBr·xH2O
    Color and Shape:White Solid
    Molecular weight:384.26

    Ref: TR-S200000

    1g
    181.00€
    5g
    473.00€
    500mg
    125.00€
  • Scopolamine-13C, D3 Hydrobromide

    Controlled Product
    CAS:
    <p>Applications Scopolamine-13C, d3 Hydrobromide, is the labeled analogue of Scopolamine-d3 Hydrobromide (S200002), an acetylcholine antagonist, used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),<br></p>
    Formula:C1613CH19D3BrNO4
    Color and Shape:Off-White
    Molecular weight:388.28

    Ref: TR-S200003

    1mg
    399.00€
    10mg
    2,723.00€
  • Scopolamine hydrobromide

    CAS:
    <p>Scopolamine hydrobromide is an anticholinergic medication, which is a derivative of tropane alkaloids sourced primarily from Solanaceae family plants, such as Hyoscyamus niger and Datura stramonium. Its mode of action involves competitive inhibition of acetylcholine at muscarinic receptors in the central and peripheral nervous systems. This blocking effect impedes parasympathetic nerve impulses, leading to diminished activity in smooth muscles and glandular secretions.</p>
    Formula:C17H21NO4·HBr
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:384.26 g/mol

    Ref: 3D-FA66263

    5g
    400.00€
    10g
    622.00€
    25g
    1,278.00€
    50g
    2,212.00€