CAS 114-49-8

Scopolamine hydrobromide

Description:

Scopolamine hydrobromide is a tropane alkaloid derived from plants of the Solanaceae family, particularly from the belladonna plant. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. The substance acts primarily as an anticholinergic agent, blocking the action of acetylcholine in the nervous system, which makes it effective in treating motion sickness, nausea, and vomiting. Scopolamine hydrobromide is also used in preoperative settings to reduce salivation and secretions. Its pharmacological effects include sedation, amnesia, and muscle relaxation, but it can also cause side effects such as dry mouth, blurred vision, and drowsiness. Due to its potential for abuse and the risk of severe side effects, its use is carefully monitored in clinical settings. As with any medication, it is essential to use scopolamine hydrobromide under the guidance of a healthcare professional to ensure safety and efficacy.

Formula: C₁₇H₂₂BrNO₄

InChI: InChI=1/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13+,14?,15-,16?;/m1./s1

InChI key: InChIKey=WTGQALLALWYDJH-MOUKNHLCSA-N

SMILES: CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].Br

Synonyms:

• (-)-Scopolamine bromide
• (-)-Scopolamine, HBr
• (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl 3-hydroxy-2-phenylpropanoate hydrobromide (1:1)
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
• 3-Oxa-9-azatricyclo[3.3.1.0^2,4]nonane, benzeneacetic acid deriv.
• 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrobromide (1:1)
• 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrochloride
• Beldavrin
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide (1:1), (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
• Euscopol
• Hydroscine hydrobromide
• Hyocine f hydrobromide
• Hyoscine Hydrobromide
• Hyoscine bromide
• Hysco
• Isoscopil
• Kwells
• Scopamin
• Scopolamine hydrobromide
• Scopolaminium bromide
• Scopolammonium bromide
• Scopos
• Sea Legs
• Sereen
• Triptone
• Wellcome Brand Scopolamine hydrobromide Injection
• benzeneacetic acid, alpha-(hydroxymethyl)-, bromide, (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl ester, (alphaS)-
• l-Hyoscine hydrobromide
• l-Scopolamine hydrobromide
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide (1:1), (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, (αS)-
• scopolamine hydrobromide trihydrate
• 1αH,5αH-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
• HYOSCINE
• ),hydrobromide
• (A,S)-ALPHA-(HYDROXYMETHYL)BENZENEACETIC ACID (1A,2B,4B,5A,7B)-9-METHYL-3-OXA-9-AZATRICYCLO[3.3.1.02,4]NON-7-YL ESTER HYDROBROMIDE
• alpha-(hydroxymethyl)-benzeneaceticaci9-methyl-3-oxa-9-azatricyclo[3.3.1.
• SCOPINE TROPATE HYDROBROMIDE
• HYOSCINE HBR
• SCOPOLOAMINE HYDROBROMIDE
• .alpha.-(hydroxymethyl)-,9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester,hydrobromide,[7(Benzeneaceticacid
• hydroscinehydrobromide
• ATROSCINE HYDROBROMIDE
• hyocinefhydrobromide
• 5-alpha-h-tropan-3-alpha-ol,6-beta,7-beta-epoxy-1-alpha-(-)-tropate(ester
• (-)-scopolaminebromide

Scopolamine HBr (Hyoscine HBr)

CAS: 114-49-8

Formula: C₁₇H₂₁NO₄·HBr

Color and Shape: White To Off-White Solid

Molecular weight: 303.36 80.91

Ref: 4Z-S-012

Scopolamine hydrobromide

CAS: 114-49-8

Formula: C₁₇H₂₂BrNO₄

Purity: 95%~99%

Molecular weight: 384.27

Ref: BP-BP1274

Scopolamine Hydrobromide Trihydrate

CAS: 114-49-8, 51-34-3, 6533-68-2

Formula: C₁₇H₂₁NO₄·HBr·3H₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 438.32

Ref: 3B-S0021

(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide

CAS: 114-49-8

(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide

Purity: ≥95%

Molecular weight: 438.31g/mol

Ref: 54-OR310495

Scopolamine hydrobromide

CAS: 114-49-8

Natural alkaloid

Formula: C₁₇H₂₁NO₄HBr

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 384.27

Ref: 5G-80046

Scopolamine Hydrobromide Hydrate

Controlled Product

CAS: 114-49-8, 6533-68-2

Applications Scopolamine Hydrobromide Hydrate is an acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Neuroprotective & Neuroresearch Product.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brand, J.J., et al.: Lancet, 2, 232 (1970); Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979); Clissold, S.P., et al.: Drugs, 29, 189 (1985); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990);

Formula: C₁₇H₂₁NO₄·HBr·xH₂O

Color and Shape: White Solid

Molecular weight: 384.26

Ref: TR-S200000

Scopolamine-13C, D3 Hydrobromide

Controlled Product

CAS: 114-49-8

Applications Scopolamine-13C, d3 Hydrobromide, is the labeled analogue of Scopolamine-d3 Hydrobromide (S200002), an acetylcholine antagonist, used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),

Formula: C₁₆₁₃CH₁₉D₃BrNO₄

Color and Shape: Off-White

Molecular weight: 388.28

Ref: TR-S200003

Scopolamine hydrobromide

CAS: 114-49-8

Scopolamine hydrobromide is an anticholinergic medication, which is a derivative of tropane alkaloids sourced primarily from Solanaceae family plants, such as Hyoscyamus niger and Datura stramonium. Its mode of action involves competitive inhibition of acetylcholine at muscarinic receptors in the central and peripheral nervous systems. This blocking effect impedes parasympathetic nerve impulses, leading to diminished activity in smooth muscles and glandular secretions.

Formula: C₁₇H₂₁NO₄·HBr

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 384.26 g/mol

Ref: 3D-FA66263