CAS 114-80-7: Neostigmine bromide

Description: Neostigmine bromide is a synthetic compound classified as a reversible inhibitor of the enzyme acetylcholinesterase, which plays a crucial role in the breakdown of the neurotransmitter acetylcholine. This compound is primarily used in the treatment of myasthenia gravis, a neuromuscular disorder characterized by weakness and rapid fatigue of voluntary muscles. Neostigmine bromide is a quaternary ammonium compound, which means it has a positively charged nitrogen atom, contributing to its solubility in water and limiting its ability to cross the blood-brain barrier. The substance typically appears as a white to off-white crystalline powder and is known for its relatively low toxicity when used appropriately. Its pharmacological effects include increased muscle strength and improved neuromuscular transmission. Additionally, neostigmine bromide can be used in certain surgical settings to reverse the effects of neuromuscular blocking agents. As with any medication, it is essential to monitor for potential side effects, including gastrointestinal disturbances and increased salivation.

Formula: C₁₂H₁₉N₂O₂·Br

InChI: InChI=1S/C12H19N2O2.BrH/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;/h6-9H,1-5H3;1H/q+1;/p-1

InChI key: InChIKey=LULNWZDBKTWDGK-UHFFFAOYSA-M

SMILES: [Br-].O=C(OC1=CC=CC(=C1)[N+](C)(C)C)N(C)C

Synonyms:

• (3-Dimethylcarbamoyloxyphenyl)trimethylammonium bromide
• (m-Hydroxyphenyl)trimethylammonium bromide, dimethylcarbamate
• 3-[(Dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium bromide
• Ammonium, (m-hydroxyphenyl)trimethyl-, bromide, dimethylcarbamate
• Amostigmine
• Benzenaminium, 3-[[(dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-, bromide
• Carbamic acid, dimethyl-, ester with (m-hydroxyphenyl)trimethylammonium bromide
• Eustigmin bromide
• Kirkstigmine bromide
• Neoeserine bromide
• Neoesserin
• Philostigmin bromide
• Prostigmin bromide
• Prostigmine bromide
• Stigmanol bromide
• Stigmosan bromide
• Syntostigmin (tablet)
• Syntostigmin bromide
• Vagostigmine bromide
• benzenaminium, 3-[[(dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-, bromide (1:1)
• Neostigmine bromide

Neostigmine Bromide

CAS: 114-80-759-99-4

• Formula: C₁₂H₁₉BrN₂O₂
• Purity: >99.0%(T)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 303.20

Neostigmine bromide

CAS: 114-80-7

A reversible acetylcholinesterase inhibitor This Thermo Scientific Chemicals brand product was originally part of the …

• Formula: C₁₂H₁₉BrN₂O₂
• Color and Shape: White to off-white, Powder or crystals or crystalline powder
• Molecular weight: 303.2

Neostigmine bromide CRS

CAS: 114-80-7

• Formula: C₁₂H₁₉BrN₂O₂
• Color and Shape: Crystalline Powder. White. Colourless. Powder.
• Molecular weight: 303.1955

Neostigmine Bromide

CAS: 114-80-7

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

• Formula: C₁₂H₁₉BrN₂O₂
• Color and Shape: White Crystalline Powder
• Molecular weight: 302.06299

Neostigmine Bromide

CAS: 114-80-7

• Formula: C₁₂H₁₉BrN₂O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 303.1955

Neostigmine bromide

CAS: 114-80-7

Neostigmine bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to …

• Formula: C₁₂H₁₉BrN₂O₂
• Purity: 98.02%
• Color and Shape: White Powder
• Molecular weight: 303.2

Neostigmine Bromide

CAS: 114-80-7

• Formula: C₁₂H₁₉N₂O₂·Br
• Color and Shape: Neat
• Molecular weight: 303.20

Neostigmine bromide

CAS: 114-80-7

• Formula: C₁₂H₁₉BrN₂O₂
• Molecular weight: 303.20

Neostigmine bromide

CAS: 114-80-7

• Purity: 98.0%
• Molecular weight: 303.20001220703125

Neostigmine Bromide

CAS: 114-80-7

Applications Cholinergic; miotic; antidote (curare). Not a dangerous good if item is equal to or …

• Formula: C₁₂H₁₉N₂O₂·Br
• Color and Shape: Neat
• Molecular weight: 303.20

Neostigmine bromide

CAS: 114-80-7

Inhibitor of acetylcholinesterase

• Formula: C₁₂H₁₉BrN₂O₂
• Purity: Min. 95%
• Molecular weight: 303.2 g/mol