CAS 114-80-7
:Neostigmine bromide
Description:
Neostigmine bromide is a synthetic compound classified as a reversible inhibitor of the enzyme acetylcholinesterase, which plays a crucial role in the breakdown of the neurotransmitter acetylcholine. This compound is primarily used in the treatment of myasthenia gravis, a neuromuscular disorder characterized by weakness and rapid fatigue of voluntary muscles. Neostigmine bromide is a quaternary ammonium compound, which means it has a positively charged nitrogen atom, contributing to its solubility in water and limiting its ability to cross the blood-brain barrier. The substance typically appears as a white to off-white crystalline powder and is known for its relatively low toxicity when used appropriately. Its pharmacological effects include increased muscle strength and improved neuromuscular transmission. Additionally, neostigmine bromide can be used in certain surgical settings to reverse the effects of neuromuscular blocking agents. As with any medication, it is essential to monitor for potential side effects, including gastrointestinal disturbances and increased salivation.
Formula:C12H19N2O2·Br
InChI:InChI=1S/C12H19N2O2.BrH/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;/h6-9H,1-5H3;1H/q+1;/p-1
InChI key:InChIKey=LULNWZDBKTWDGK-UHFFFAOYSA-M
SMILES:O(C(N(C)C)=O)C1=CC([N+](C)(C)C)=CC=C1.[Br-]
Synonyms:- (3-Dimethylcarbamoyloxyphenyl)trimethylammonium bromide
- (m-Hydroxyphenyl)trimethylammonium bromide, dimethylcarbamate
- 3-[(Dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium bromide
- Ammonium, (m-hydroxyphenyl)trimethyl-, bromide, dimethylcarbamate
- Amostigmine
- Benzenaminium, 3-[[(dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-, bromide
- Carbamic acid, dimethyl-, ester with (m-hydroxyphenyl)trimethylammonium bromide
- Eustigmin bromide
- Kirkstigmine bromide
- Neoeserine bromide
- Neoesserin
- Philostigmin bromide
- Prostigmin bromide
- Prostigmine bromide
- Stigmanol bromide
- Stigmosan bromide
- Syntostigmin (tablet)
- Syntostigmin bromide
- Vagostigmine bromide
- benzenaminium, 3-[[(dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-, bromide (1:1)
- See more synonyms
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Found 13 products.
Neostigmine bromide
CAS:<p>A reversible acetylcholinesterase inhibitor</p>Formula:C12H19BrN2O2Color and Shape:White to off-white, Powder or crystals or crystalline powderMolecular weight:303.2NEOSTIGMINE BROMIDE CRS
CAS:NEOSTIGMINE BROMIDE CRSFormula:C12H19BrN2O2Color and Shape:Crystalline Powder. White. Colourless. Powder.Molecular weight:303.1955Neostigmine Bromide
CAS:Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereofFormula:C12H19BrN2O2Color and Shape:White Crystalline PowderMolecular weight:302.06299Neostigmine bromide
CAS:Neostigmine bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.Formula:C12H19BrN2O2Purity:98.02% - 98.39%Color and Shape:White PowderMolecular weight:303.2Neostigmine Bromide
CAS:Controlled ProductFormula:C12H19N2O2·BrColor and Shape:NeatMolecular weight:303.20Neostigmine Bromide
CAS:Formula:C12H19BrN2O2Purity:>99.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:303.20Neostigmine Bromide
CAS:Controlled Product<p>Applications Cholinergic; miotic; antidote (curare).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Calvey, T.N., et al.: Br. J. Clin. Pharmacol., 7, 149 (1979), Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 16, 403 (1987),<br></p>Formula:C12H19N2O2·BrColor and Shape:NeatMolecular weight:303.20Neostigmine bromide
CAS:<p>Inhibitor of acetylcholinesterase</p>Formula:C12H19BrN2O2Purity:Min. 95%Molecular weight:303.2 g/mol
