CAS 114-85-2

1-benzyl-2,3-dimethylguanidinium sulphate (2:1)

Description:

1-Benzyl-2,3-dimethylguanidinium sulfate (2:1) is a quaternary ammonium compound characterized by its guanidine structure, which features a benzyl group and two methyl groups attached to the nitrogen atoms. This compound is typically used in various chemical applications, including as a reagent in organic synthesis and as a phase transfer catalyst. It exhibits good solubility in polar solvents due to the presence of the sulfate group, which enhances its ionic character. The guanidinium moiety contributes to its basicity and potential biological activity, making it of interest in medicinal chemistry. Additionally, the compound may display surface-active properties, which can be beneficial in formulations requiring emulsification or stabilization. Its stability under standard laboratory conditions allows for ease of handling, although care should be taken regarding its reactivity with strong acids or bases. Overall, 1-benzyl-2,3-dimethylguanidinium sulfate (2:1) is a versatile compound with applications in both research and industrial settings.

Formula: C₁₀H₁₅N₃H₂O₄S

InChI: InChI=1S/C10H15N3.H2O4S/c1-11-10(12-2)13-8-9-6-4-3-5-7-9;1-5(2,3)4/h3-7H,8H2,1-2H3,(H2,11,12,13);(H2,1,2,3,4)

InChI key: InChIKey=WDLCALUKNKNIDF-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)O.C(N=C(NC)NC)C1=CC=CC=C1

Synonyms:

• 1-Benzyl-2,3-dimethylguanidine hemisulfate
• 1-Benzyl-2,3-dimethylguanidine sulfate
• 1-Benzyl-2,3-dimethylguanidinium sulfate
• Batel
• Bendogen
• Benzaidin
• Benzanidin
• Benzanidine
• Betanidine sulfate
• Betanidol
• Betanidole
• Bethanid
• Bethanidine Sulfate
• Bethanidine hemisulfate
• Bw 467C60
• Esbatal
• Eusmanid
• Guanidine, 1-benzyl-2,3-dimethyl-, sulfate (2:1)
• Guanidine, N,N′-dimethyl-N′′-(phenylmethyl)-, sulfate (2:1)
• Hypersin
• NSC 106563
• Regulin
• Tenathan

Bethanidine sulfate

CAS: 114-85-2

Bethanidine sulfate and its ortho-chloro derivative (BW 392C60) are potent adrenergic neuron blockers exhibiting sympathomimetic effects similar to those of bromobenzamine and guanethidine in various animal models, particularly in cats. These compounds inhibit the release of norepinephrine during neural stimulation and enhance the responsiveness of smooth muscle to epinephrine and norepinephrine. Notably, bethanidine sulfate increases the pressor response to tyramine, although this effect diminishes with higher doses. Unlike guanethidine, bethanidine sulfate does not deplete pressor amines in the iris of cats following administration. Additionally, it temporarily suppresses autonomic cholinergic mechanisms and can cause transient neuromuscular paralysis at large doses, contrasting its long-term adrenergic neuron blocking effects.

Formula: C₂₀H₃₂N₆O₄S

Color and Shape: Solid

Molecular weight: 452.57

Ref: TM-T88551

Bethanidine Sulfate

CAS: 114-85-2

Color and Shape: Neat

Ref: 61-FOR1834.00