CAS 114056-26-7

vasotocin, (beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)-O-methyl-Tyr(2)-Thr(4)-Orn(8)-Tyr(9)-NH2

Description:

Vasotocin is a peptide hormone that plays a significant role in various physiological processes, particularly in regulating water balance and blood pressure. It is structurally related to vasopressin and oxytocin, featuring a cyclic structure that enhances its stability and biological activity. The specific sequence of amino acids in vasotocin includes modifications such as beta-mercapto-beta,beta-cyclopentamethylenepropionic acid, which contributes to its unique properties. This compound exhibits strong affinity for vasopressin receptors, influencing renal function and vascular tone. Additionally, vasotocin is involved in social behaviors and stress responses in certain species. Its CAS number, 114056-26-7, identifies it uniquely in chemical databases, facilitating research and application in pharmacology and biochemistry. The presence of specific amino acid residues, such as O-methyl-Tyr and Orn, indicates potential for varied interactions within biological systems, making it a subject of interest in studies related to neuroendocrinology and therapeutic development. Overall, vasotocin's characteristics underscore its importance in both basic and applied biological sciences.

Formula: C₅₄H₇₉N₁₁O₁₃S₂

InChI: InChI=1/C54H79N11O13S2/c1-5-30(2)44(63-49(73)38(26-32-13-17-34(67)18-14-32)58-43(69)28-54(80)21-7-6-8-22-54)51(75)64-45(31(3)66)52(76)61-39(27-42(56)68)48(72)62-40(29-79)53(77)65-24-10-12-41(65)50(74)59-36(11-9-23-55)47(71)60-37(46(57)70)25-33-15-19-35(78-4)20-16-33/h13-20,29-31,36-41,44-45,66-67,80H,5-12,21-28,55H2,1-4H3,(H2,56,68)(H2,57,70)(H,58,69)(H,59,74)(H,60,71)(H,61,76)(H,62,72)(H,63,73)(H,64,75)/t30-,31+,36-,37-,38-,39-,40-,41-,44-,45-/m0/s1

Synonyms:

• 1-d(CH2)5-2-(O-Methyl)-tyrosyl-4-theonyl-8-ornithyl-9-tyrosinamide-vasotocin
• N-((1-Mercaptocyclohexyl)acetyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-L-tyrosinamide cyclic (1-5)-disulfide
• Ovta
• Ota-vasotocin
• d(CH2)5-O-Methyl-tyrosyl(2)-threonyl(4)-ornithyl(8)-tyrosinamide(9)-vasotocin
• d(CH2)5-Tyr(Me)(2)-thr(4)-orn(8)-tyr(9)-NH2-vasotocin
• L-Tyrosinamide, N-((1-mercaptocyclohexyl)acetyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-, cyclic (1-5)-disulfide
• N-[(1-sulfanylcyclohexyl)acetyl]-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-3-thioxo-L-alanyl-L-prolyl-L-ornithyl-O-methyl-L-tyrosinamide
• Vasotocin, (beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)-O-methyl-tyr(2)-thr(4)-orn(8)-tyr(9)-NH2
• b-Mercapto-b,b-cyclopentaMethylene-propionyl-Tyr(Me)-Ile-Thr-Asn-Cys-Pro-Orn-Tyr-NH2
• (2S)-N-[(2R)-1-[(2S)-2-[[(2S)-5-amino-1-[[(2S)-1-amino-3-(4-methoxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylidenepropan-2-yl]-2-[[(2S,3R)-3-hydroxy-2-[[(2S,3S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[2-(1-sulfanylcyclohexyl)acetyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]butanoyl]amino]butanediamide
• (2S)-N-[(2R)-1-[(2S)-2-[[(2S)-5-amino-1-[[(2S)-1-amino-3-(4-methoxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylidenepropan-2-yl]-2-[[(2S,3R)-3-hydroxy-2-[[(2S,3S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[2-(1-sulfan

(d(CH₂)₅¹,Tyr(Me)²,Thr⁴,Orn⁸,Tyr-NH₂⁹)-Vasotocin

CAS: 114056-26-7

The oxytocin antagonist OVTA shows enhanced affinity for rat uterine oxytocin receptors after iodination.

Formula: C₅₄H₇₉N₁₁O₁₃S₂

Purity: 98.7%

Color and Shape: White Powder

Molecular weight: 1154.42

Ref: 01-4015938

(d(CH2)51,Tyr(Me)2,Thr4, Orn 8,Tyr-NH29)-Vasotocin trifluoroacetate salt

CAS: 114056-26-7

Vasotocin is a peptide that belongs to the family of arginine vasotocin and oxytocin receptor antagonists. It is synthesized in the rat kidney, where it is stored in vesicles. Vasotocin has been shown to bind to the oxytocin receptor, which regulates many physiological processes such as muscle contraction, ejaculation, and milk letdown. Vasotocin also modulates the activity of antigen-presenting cells and can be used for pharmaceutical formulations. This drug has been shown to be effective against congestive heart failure and may be used as a diluent for other drugs.br>br>
Vasotocin trifluoroacetate salt (VT) is an oxime derivative that can be isolated from vasotocin. The synthesis of VT involves converting vasotocin into its trifluoroacetate salt by adding trifluoroacetic acid, followed by reacting with hydroxylam

Formula: C₅₄H₇₉N₁₁O₁₃S₂

Purity: Min. 95%

Molecular weight: 1,154.4 g/mol

Ref: 3D-FT110427