CAS: 1140909-48-3 - cabozantinib (S)-malate

Formula: C₂₈H₂₄FN₃O₅.C₄H₆O₅

InChI: InChI=1S/C28H24FN3O5.C4H6O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18;5-2(4(8)9)1-3(6)7/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34);2,5H,1H2,(H,6,7)(H,8,9)/t;2-/m.0/s1

InChI key: InChIKey=HFCFMRYTXDINDK-WNQIDUERSA-N

SMILES: O=C(O)CC(O)C(=O)O.O=C(NC1=CC=C(F)C=C1)C2(C(=O)NC3=CC=C(OC=4C=CN=C5C=C(OC)C(OC)=CC54)C=C3)CC2

Synonyms:

• (2S)-2-Hydroxybutanedioic acid compd.with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide(1:1)
• (2S)-2-hydroxybutanedioic acid
• Butanedioic acid, 2-hydroxy-, (2S)-, compd. with N-[4-[(6,7-dimethoxy-4- quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)
• Cabozantinib L-(-)-Apple Acid
• Cabozantinib L-Malate
• Cabozantinib Malate
• Cometriq
• N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide mono[(2S)-2-hydroxybutanedioate]
• N1-[4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N1'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• Xl 184

Butanedioic acid, 2-hydroxy-, (2S)-, compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)

CAS: 1140909-48-3

• Formula: C₃₂H₃₀FN₃O₁₀
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 635.5931

Cabozantinib (S)-Malate

CAS: 1140909-48-3

• Formula: C₂₈H₂₄FN₃O₅·C₄H₆O₅
• Color and Shape: White To Off-White Solid
• Molecular weight: 501.51 134.09

Cabozantinib (S)-Malate

CAS: 1140909-48-3

• Formula: C₂₈H₂₄FN₃O₅·C₄H₆O₅
• Color and Shape: Neat
• Molecular weight: 635.59

Cabozantinib S-malate

CAS: 1140909-48-3

Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK …

• Formula: C₃₂H₃₀FN₃O₁₀
• Purity: 100% - 98.87%
• Color and Shape: Solid
• Molecular weight: 635.59

Cabozantinib malate

CAS: 1140909-48-3

• Formula: C₃₂H₃₀FN₃O₁₀
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 635.59

Cabozantinib (Phenylene-d4) L-Malate Salt

CAS: 1140909-48-3

Applications Cabozantinib-d4 L-Malate Salt, is the labeled analogue of Cabozantinib L-Malate Salt (C051500), which is …

• Formula: C₂₈D₄H₂₀FN₃O₅·C₄H₆O₅
• Color and Shape: Neat
• Molecular weight: 639.62

Cabozantinib L-Malate Salt

CAS: 1140909-48-3

Applications Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, …

• Formula: C₂₈H₂₄FN₃O₅·C₄H₆O₅
• Color and Shape: Neat
• Molecular weight: 635.59

Cabozantinib malate

CAS: 1140909-48-3

Inhibits MET, VEGFR1, VEGFR2; VEGFR3 receptor tyrosine kinases; antineoplastic

• Formula: C₂₈H₂₄FN₃O₅·C₄H₆O₅
• Purity: Min. 95%
• Color and Shape: Off-White Powder
• Molecular weight: 635.6 g/mol