CAS 1141397-80-9: Cedazuridine

Description: Cedazuridine, also known by its chemical name, is a nucleoside analog that functions primarily as an inhibitor of cytidine deaminase, an enzyme that degrades cytidine and its analogs. This characteristic enhances the bioavailability and efficacy of certain chemotherapeutic agents, particularly in the treatment of cancer. Cedazuridine is often used in combination with other drugs to improve their therapeutic effects while reducing toxicity. The compound is typically administered orally and is known for its role in enhancing the pharmacokinetics of nucleoside analogs, allowing for lower doses and potentially fewer side effects. Its mechanism of action involves the prevention of the conversion of cytidine to uridine, thereby increasing the levels of active nucleoside analogs in the body. Cedazuridine has been studied in various clinical settings, particularly in hematological malignancies, and continues to be an area of interest in cancer research for its potential to improve treatment outcomes.

Synonyms:

• (R)-1-((2R, 4R, SR)-3,3-difluoro-4-hydroxy (hydroxymethyl) tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one

Cedazuridine

CAS: 1141397-80-9

• Formula: C₉H₁₄F₂N₂O₅
• Molecular weight: 268.22

Cedazuridine

CAS: 1141397-80-9

Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.

• Formula: C₉H₁₄F₂N₂O₅
• Purity: 99.46%
• Color and Shape: Solid
• Molecular weight: 268.21

Cedazuridine

CAS: 1141397-80-9

Cedazuridine (also known as NUC-1031) is a small molecule that is being studied as a …

• Formula: C₉H₁₄F₂N₂O₅
• Purity: Min. 95%
• Molecular weight: 268.21 g/mol