CAS 114176-52-2

2-carboxyarticaine

Description:

2-Carboxyarticaine is a chemical compound that belongs to the class of local anesthetics, specifically a derivative of articaine. It features a carboxylic acid functional group, which contributes to its solubility and pharmacological properties. The compound is characterized by its ability to block nerve conduction, making it useful in dental procedures and other medical applications requiring localized anesthesia. Its structure includes an aromatic ring, an amine group, and an ester linkage, which are typical of local anesthetics. The presence of the carboxylic acid group may enhance its interaction with biological tissues and influence its metabolic pathways. 2-Carboxyarticaine is known for its relatively rapid onset of action and moderate duration of effect, similar to other anesthetics in its class. Additionally, it may exhibit lower toxicity compared to traditional anesthetics, making it a subject of interest in research for improved anesthetic formulations. As with all chemical substances, safety and efficacy are paramount, and its use should be guided by appropriate medical protocols.

Formula: C₁₂H₁₈N₂O₃S

InChI: InChI=1/C12H18N2O3S/c1-4-5-13-8(3)11(15)14-9-7(2)6-18-10(9)12(16)17/h6,8,13H,4-5H2,1-3H3,(H,14,15)(H,16,17)

SMILES: CCCNC(C)C(=Nc1c(C)csc1C(=O)O)O

Synonyms:

• Articainic acid
• 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-
• 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylic acid
• 2-Carboxyarticaine

Articaine Related Compound B (4-methyl-3-{[2-(propylamino)propanoyl]amino}thiophene-2-carboxylic acid)

CAS: 114176-52-2

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₂H₁₈N₂O₃S

Color and Shape: Powder

Molecular weight: 270.10381

Ref: 45-1042930

4-methyl-3-[2-(propylamino)propanamido]thiophene-2-carboxylic acid

CAS: 114176-52-2

Formula: C₁₂H₁₈N₂O₃S

Color and Shape: Solid

Molecular weight: 270.3479

Ref: IN-DA000AQL

Articaine EP Impurity B HCl (Articaine Acid HCl)

CAS: 114176-52-2

Formula: C₁₂H₁₈N₂O₃S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 270.35 36.46

Ref: 4Z-A-156003

4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid

Controlled Product

CAS: 114176-52-2

Applications 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid is an impurity of Articaine (A777900), an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand , food surgery and in dentistry.
References Grossman, M., et al.: J. Clin. Pharmacol., 44, 1282 (2004); Oertel, R., et al.: Pharmazie., 53, 646 (1998); Vree, T.B., et al.: Brit. J. Clin. Pharmacol., 44, 29 (1997);

Formula: C₁₂H₁₈N₂O₃S·ClH

Color and Shape: White To Off-White

Molecular weight: 306.81

Ref: TR-M326815

4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid-d3

Controlled Product

CAS: 114176-52-2

Formula: C₁₂D₃H₁₅N₂O₃S

Color and Shape: Neat

Molecular weight: 273.366

Ref: TR-M326817

4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid-d7

Controlled Product

CAS: 114176-52-2

Applications 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid-d7 is the labelled form of 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid (M326815). 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid is an impurity of Articaine (A777900), an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry.
References Grossman, M., et al.: J. Clin. Pharmacol., 44, 1282 (2004); Oertel, R., et al.: Pharmazie., 53, 646 (1998); Vree, T.B., et al.: Brit. J. Clin. Pharmacol., 44, 29 (1997)

Formula: C₁₂H₁₁D₇N₂O₃S

Color and Shape: Neat

Molecular weight: 277.39

Ref: TR-M326816

Articaine EP Impurity B

CAS: 114176-52-2

Formula: C₁₂H₁₈N₂O₃S

Molecular weight: 270.35

Ref: ST-EA-CP-A83002