Etravirine-d6 is a deuterated form of Etravirine, an antiretroviral medication used primarily in the treatment of HIV infection. As a non-nucleoside reverse transcriptase inhibitor (NNRTI), Etravirine works by binding to the reverse transcriptase enzyme, thereby inhibiting viral replication. The "d6" designation indicates that the compound contains six deuterium atoms, which are isotopes of hydrogen, replacing the regular hydrogen atoms in the molecular structure. This modification can enhance the stability and tracking of the compound in various studies, particularly in pharmacokinetics and metabolic research. Etravirine-d6 retains similar pharmacological properties to its non-deuterated counterpart, making it useful in research settings to investigate drug metabolism and interactions. The compound is typically characterized by its molecular formula, molecular weight, and specific spectral properties, which can be analyzed using techniques such as NMR spectroscopy. Overall, Etravirine-d6 serves as a valuable tool in the study of HIV treatment and drug development.

Etravirine-d6

1142096-06-7: Etravirine-d6 is a deuterated form of Etravirine, an antiretroviral medication used primarily in the treatment of HIV infection. As a non-nucleoside reverse transcriptase inhibitor (NNRTI), Etravirine works by binding to the reverse transcriptase enzyme, thereby inhibiting viral replication. The "d6" designation indicates that the compound contains six deuterium atoms, which are isotopes of hydrogen, replacing the regular hydrogen atoms in the molecular structure. This modification can enhance the stability and tracking of the compound in various studies, particularly in pharmacokinetics and metabolic research. Etravirine-d6 retains similar pharmacological properties to its non-deuterated counterpart, making it useful in research settings to investigate drug metabolism and interactions. The compound is typically characterized by its molecular formula, molecular weight, and specific spectral properties, which can be analyzed using techniques such as NMR spectroscopy. Overall, Etravirine-d6 serves as a valuable tool in the study of HIV treatment and drug development.

<p>Applications A novel labelled HIV reverse transcriptase inhibitor useful in treatment of HIV infection.<br>References Scholler-Gyure, M., et al.: J. Clin. Pharmacol., 48, 322 (2008), Thakur, A., et al.: Eur. J. Med. Chem., 43, 471 (2008),<br></p>

CAS 1142096-06-7

Etravirine-d6

Etravirine-d8

Ref: TR-E937003