CAS 114247-09-5

(-)-Fluoxetine hydrochloride

Description:

(-)-Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI) primarily used as an antidepressant in the treatment of major depressive disorder, obsessive-compulsive disorder, and certain anxiety disorders. It is the hydrochloride salt form of fluoxetine, which is characterized by its chiral nature, with the (-) enantiomer being the active form. The compound has a molecular formula that includes carbon, hydrogen, nitrogen, oxygen, and chlorine, reflecting its complex structure. It is typically presented as a white to off-white crystalline powder, soluble in water and methanol, but less soluble in organic solvents like chloroform. The mechanism of action involves the inhibition of serotonin reuptake in the brain, leading to increased serotonin levels in the synaptic cleft, which is believed to contribute to its antidepressant effects. Common side effects may include nausea, insomnia, and sexual dysfunction. Due to its pharmacological properties, (-)-Fluoxetine hydrochloride is a widely studied and utilized medication in psychiatric practice.

Formula: C₁₇H₁₈F₃NO·ClH

InChI: InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1

InChI key: InChIKey=GIYXAJPCNFJEHY-PKLMIRHRSA-N

SMILES: [C@@H](OC1=CC=C(C(F)(F)F)C=C1)(CCNC)C2=CC=CC=C2.Cl

Synonyms:

• (-)-Fluoxetine hydrochloride
• (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride (1:1)
• (R)-3-[4(Trifluoromethyl)Phenoxy]-N-Methyl-3-Phenylpropan-1-Amine Hydrochloride
• (R)-Fluoxetine
• (R)-N-Methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine hydrochloride
• Benzenepropanamine, N-methyl-γ-[4-(trifluoromethyl)phenoxy]-, hydrochloride (1:1), (γR)-
• Benzenepropanamine, N-methyl-γ-[4-(trifluoromethyl)phenoxy]-, hydrochloride, (R)-
• Benzenepropanamine, N-methyl-γ-[4-(trifluoromethyl)phenoxy]-, hydrochloride, (γR)-
• (R)-Fluoxetine hydrochloride
• (R)-(-)-Fluoxetine hydrochloride

Benzenepropanamine, N-methyl-γ-[4-(trifluoromethyl)phenoxy]-, hydrochloride (1:1), (γR)-

CAS: 114247-09-5

Formula: C₁₇H₁₉ClF₃NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 345.7871

Ref: IN-DA000AWL

R-(-)-Fluoxetine hydrochloride

CAS: 114247-09-5

Formula: C₁₇H₁₈NOF₃·HCl

Molecular weight: 345.79

Ref: 7W-GP7054

(R)-Fluoxetine Hydrochloride

Controlled Product

CAS: 114247-09-5

Applications A selective serotonin reuptake inhibitor (SSRI). Used as an antidepressant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wong, D.T., et al.: Life Sci., 15, 471 (1974), Goldstein, D.J., et al.: Br. J. Psychiat., 166, 660 (1995), Ni, Y.G., et al.: Proc. Nat. Acad. Sci. USA, 94, 2036 (1997)

Formula: C₁₇H₁₈F₃NO·ClH

Color and Shape: Neat

Molecular weight: 345.79

Ref: TR-F597090

(R)-Fluoxetine HCl

Controlled Product

CAS: 114247-09-5

Selective serotonin reuptake inhibitor; anti-depressant

Formula: C₁₇H₁₉ClF₃NO

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 345.79 g/mol

Ref: 3D-FF23494

(R)-Fluoxetine Hydrochloride

CAS: 114247-09-5

Formula: C₁₇H₁₈F₃NOHCl

Molecular weight: 309.33 : 36.46

Ref: ST-EA-CP-F19047