CAS 114417-84-4

NOJIRIMYCIN-1-SULFONIC ACID

Description:

Nojirimycin-1-sulfonic acid, with the CAS number 114417-84-4, is a sulfonic acid derivative of nojirimycin, a naturally occurring alkaloid. This compound is characterized by its sulfonic acid functional group, which imparts strong acidity and enhances its solubility in water. Nojirimycin itself is known for its role as an inhibitor of glycosidases, enzymes that catalyze the hydrolysis of glycosidic bonds in carbohydrates. The presence of the sulfonic acid group in Nojirimycin-1-sulfonic acid may influence its biological activity and interaction with various biomolecules. This compound is of interest in medicinal chemistry and biochemistry, particularly in the study of carbohydrate metabolism and potential therapeutic applications. Its structural features, including stereochemistry and functional groups, contribute to its reactivity and potential uses in research and pharmaceutical development. As with many sulfonic acids, it is likely to exhibit good thermal stability and may participate in various chemical reactions typical of sulfonic acids, such as nucleophilic substitutions or coupling reactions.

Formula: C₆H₁₃NO₇S

InChI: InChI=1/C6H13NO7S/c8-1-2-3(9)4(10)5(11)6(7-2)15(12,13)14/h2-11H,1H2,(H,12,13,14)/t2-,3-,4+,5-,6?/m1/s1

Synonyms:

• 5-Amino-5-Deoxy-D-Glucose-1-Sulfonic Acid
• (3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-piperidinesulfonic Acid
• Nojirimycin Bisulfite Adduct
• Nojirimycin Sulfite Adduct
• (3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)piperidine-2-sulfonic acid

2-Piperidinesulfonic acid, 3,4,5-trihydroxy-6-(hydroxymethyl)-, (3R,4S,5R,6R)-

CAS: 114417-84-4

Formula: C₆H₁₃NO₈S

Color and Shape: Solid

Molecular weight: 259.2343

Ref: IN-DA000BA7

Nojirimycin-1-Sulfonic Acid

Controlled Product

CAS: 114417-84-4

Applications An inhibitor of several glucosidases. Can be converted to Nojirimycin by treatment with Basic Resin.
References Niwa, A., et al.: Agric. Biol. Chem., 34, 966 (1970), Reese, E.T., et al.: Carbohydr. Res., 18, 381 (1971)

Formula: C₆H₁₃NO₈S

Color and Shape: Neat

Molecular weight: 259.23

Ref: TR-N635000

Nojirimycin 1-sulfonic acid

CAS: 114417-84-4

Nojirimycin 1-sulfonic acid is a synthetic compound that has been shown to be an inhibitor of glycosylation. It is a modification of nojirimycin, which is a natural product that has been used as an anti-inflammatory agent for years. Nojirimycin 1-sulfonic acid (NJA) binds to the active site of the glycosyltransferase enzyme and prevents the transfer of sugar from the donor substrate to the acceptor substrate. This inhibits the synthesis of complex carbohydrates, oligosaccharides, and polysaccharides. The fluorination on NJA's sulfonate group also makes it more soluble in water, which increases its activity.

Formula: C₆H₁₃NO₇S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 243.24 g/mol

Ref: 3D-MN45270