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CAS 114471-18-0

:

Brain natriuretic peptide

Description:
Brain natriuretic peptide (BNP) is a neurohormone primarily produced by the cardiac ventricles in response to ventricular volume expansion and pressure overload. It plays a crucial role in cardiovascular homeostasis by promoting natriuresis, diuresis, and vasodilation, which help to reduce blood pressure and fluid overload. BNP is composed of 32 amino acids and is part of the natriuretic peptide family, which includes atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). The peptide is synthesized as a prohormone, proBNP, which is cleaved to release the active BNP and an inactive fragment, NT-proBNP. BNP levels in the blood are often measured as a biomarker for heart failure, as elevated concentrations indicate increased cardiac stress and dysfunction. The CAS number 114471-18-0 uniquely identifies this peptide in chemical databases, facilitating research and clinical applications. Overall, BNP is significant in both physiological regulation and as a diagnostic tool in cardiology.
Formula:Unspecified
InChI:InChI=1/C143H244N50O42S4/c1-13-76(10)112-137(232)189-99(68-199)131(226)188-98(67-198)130(225)187-97(66-197)129(224)186-96(65-196)117(212)166-59-105(202)169-90(52-72(2)3)114(209)163-61-107(204)171-100(132(227)177-83(32-19-22-44-146)124(219)190-111(75(8)9)136(231)184-91(53-73(4)5)127(222)175-84(34-24-46-159-141(151)152)121(216)174-85(35-25-47-160-142(153)154)122(217)185-94(139(234)235)55-78-57-157-71-167-78)69-238-239-70-101(172-108(205)62-165-116(211)95(64-195)170-106(203)60-162-113(208)87(38-39-103(148)200)181-135(230)110(74(6)7)191-126(221)89(41-51-237-12)179-120(215)82(31-18-21-43-145)180-134(229)102-37-27-49-193(102)138(233)79(147)63-194)133(228)182-92(54-77-28-15-14-16-29-77)115(210)164-58-104(201)168-80(33-23-45-158-140(149)150)118(213)173-81(30-17-20-42-144)119(214)178-88(40-50-236-11)123(218)183-93(56-109(206)207)128(223)176-86(125(220)192-112)36-26-48-161-143(155)156/h14-16,28-29,57,71-76,79-102,110-112,194-199H,13,17-27,30-56,58-70,144-147H2,1-12H3,(H2,148,200)(H,157,167)(H,162,208)(H,163,209)(H,164,210)(H,165,211)(H,166,212)(H,168,201)(H,169,202)(H,170,203)(H,171,204)(H,172,205)(H,173,213)(H,174,216)(H,175,222)(H,176,223)(H,177,227)(H,178,214)(H,179,215)(H,180,229)(H,181,230)(H,182,228)(H,183,218)(H,184,231)(H,185,217)(H,186,224)(H,187,225)(H,188,226)(H,189,232)(H,190,219)(H,191,221)(H,192,220)(H,206,207)(H,234,235)(H4,149,150,158)(H4,151,152,159)(H4,153,154,160)(H4,155,156,161)/t76-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,110-,111-,112-/m0/s1
SMILES:CC[C@H](C)[C@H]1C(=N[C@@H](CO)C(=N[C@@H](CO)C(=N[C@@H](CO)C(=N[C@@H](CO)C(=NCC(=N[C@@H](CC(C)C)C(=NCC(=N[C@@H](CSSC[C@@H](C(=N[C@@H](Cc2ccccc2)C(=NCC(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](CCCCN)C(=N[C@@H](CCSC)C(=N[C@@H](CC(=O)O)C(=N[C@@H](CCCNC(=N)N)C(=N1)O)O)O)O)O)O)O)O)N=C(CN=C([C@H](CO)N=C(CN=C([C@H](CCC(=N)O)N=C([C@H](C(C)C)N=C([C@H](CCSC)N=C([C@H](CCCCN)N=C([C@@H]1CCCN1C(=O)[C@H](CO)N)O)O)O)O)O)O)O)O)C(=N[C@@H](CCCCN)C(=N[C@@H](C(C)C)C(=N[C@@H](CC(C)C)C(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](Cc1cnc[nH]1)C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O
Synonyms:
  • Atrial natriuretic peptide B
  • B-Type natriuretic peptide
  • Brain natriuretic factor
  • Brain natriuretic peptide
  • H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH (Disulfide bond)
  • Natriuretic factor, brain
  • Nesiritide Acetate
  • Nesiritide Acetate (BNP-32) Brain Natriuretic Pept
  • NesiritideAcetate
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Found 3 products.
  • CymitQuimica logo
    Indagoo
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    Brain natriuretic peptide

    CAS:
    Formula:C143H244N50O42S4
    Purity:97%
    Color and Shape:Solid
    Molecular weight:3464.0373

    Ref: IN-DA000EHQ

    1mg
    142.00€
    5mg
    269.00€
    25mg
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    50mg
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    100mg
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  • Nesiritide Acetate
    Biopurify
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    Nesiritide Acetate

    CAS:
    Formula:C143H244N50O42S4
    Purity:95%~99%
    Color and Shape:White to Off-white Powder
    Molecular weight:3464.04

    Ref: BP-BPPG051

    ne
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  • BNP (1-32), human
    Targetmol
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    BNP (1-32), human

    CAS:
    BNP (1-32), human is a brain natriuretic peptide
    Formula:C143H244N50O42S4
    Purity:98.52%
    Color and Shape:White Powder
    Molecular weight:3464.04

    Ref: TM-T21484

    1mg
    92.00€
    5mg
    251.00€
    10mg
    401.00€
    25mg
    650.00€
    50mg
    897.00€
    100mg
    1,198.00€