CAS 1145-80-8: N-(Benzyloxycarbonyl)-L-serine

Description: N-(Benzyloxycarbonyl)-L-serine, also known as Z-L-serine, is a derivative of the amino acid L-serine, characterized by the presence of a benzyloxycarbonyl (Z) protecting group on the amino group. This compound is typically a white to off-white crystalline solid and is soluble in polar organic solvents such as methanol and dimethyl sulfoxide, but less soluble in non-polar solvents. It is commonly used in peptide synthesis as a protecting group for the amino group, allowing for selective reactions at the carboxyl group or side chains. The Z group can be removed under mild acidic conditions, facilitating the deprotection of the amino group when needed. N-(Benzyloxycarbonyl)-L-serine is also of interest in biochemical research and pharmaceutical applications due to its role in the synthesis of peptides and proteins. Its molecular structure includes a chiral center, making it optically active, and it exhibits properties typical of amino acids, such as the ability to participate in hydrogen bonding and form zwitterionic species in solution.

Formula: C₁₁H₁₃NO₅

InChI: InChI=1S/C11H13NO5/c13-6-9(10(14)15)12-11(16)17-7-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,12,16)(H,14,15)/t9-/m0/s1

InChI key: InChIKey=GNIDSOFZAKMQAO-VIFPVBQESA-N

SMILES: O=C(O)C(NC(=O)OCC=1C=CC=CC1)CO

Synonyms:

• (2S)-2-[(Benzyloxycarbonyl)amino]-3-hydroxypropanoic acid
• (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-hydroxypropanoic acid
• (2S)-3-Hydroxy-2-(phenylmethoxycarbonylamino)propanoic acid
• (S)-2-(Benzyloxycarbonylamino)-3-hydroxypropanoic acid
• <span class="text-smallcaps">L</span>-Carbobenzyloxy serine
• <span class="text-smallcaps">L</span>-Serine, N-[(phenylmethoxy)carbonyl]-
• <span class="text-smallcaps">L</span>-Serine, N-carboxy-, N-benzyl ester
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-serine
• Cbz-L-serine
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-serine
• N-Benzyloxycarbonyl-L-serine
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-serine
• N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-serine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-serine
• N-[(Phenylmethoxy)carbonyl]serine
• N-[(benzyloxy)carbonyl]-L-serine
• N-[(benzyloxy)carbonyl]serine
• N-cbz-l-serine
• NSC 286604
• Serine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• Z-Ser-OH
• L-Serine, N-[(phenylmethoxy)carbonyl]-
• L-Serine, N-carboxy-, N-benzyl ester
• N-[(Phenylmethoxy)carbonyl]-L-serine
• Serine, N-carboxy-, N-benzyl ester, L-

N-Benzyloxycarbonyl-L-serine

CAS: 1145-80-8

• Formula: C₁₁H₁₃NO₅
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 239.23

N-Benzyloxycarbonyl-L-serine, 99%

CAS: 1145-80-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₁₁H₁₃NO₅
• Purity: 99%
• Color and Shape: Powder, White
• Molecular weight: 239.23

Z-Ser-OH

CAS: 1145-80-8

Educt in Hoveyda’s synthesis of L-3-fluoroalanine and N-methyl-L-3-fluoroalanine derivatives via the oxazolidinone.

• Formula: C₁₁H₁₃NO₅
• Purity: > 99%
• Color and Shape: White
• Molecular weight: 239.23

L-Serine, N-[(phenylmethoxy)carbonyl]-

CAS: 1145-80-8

• Formula: C₁₁H₁₃NO₅
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 239.22462000000004

Z-Ser-OH

CAS: 1145-80-8

• Formula: C₁₁H₁₃NO₅
• Molecular weight: 239.23

Carbobenzyloxy-l-serine

CAS: 1145-80-8

• Purity: 97%
• Molecular weight: 239.22g/mol

N-Carbobenzyloxy-L-serine, 99+%

CAS: 1145-80-8

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₁H₁₃NO₅
• Purity: 99+%
• Color and Shape: Powder, White to cream
• Molecular weight: 239.23

Z-Ser-OH

CAS: 1145-80-8

M03053 - Z-Ser-OH

• Formula: C₁₁H₁₃NO₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 239.2270050048828

Z-L-Serine extrapure, 99%

CAS: 1145-80-8

• Formula: C₁₁H₁₃NO₅
• Purity: min. 99%
• Color and Shape: White to Cream powder, Crystalline powder
• Molecular weight: 239.2

N-Carboxybenzyl-L-serine-13C3

CAS: 1145-80-8

Applications is an intermediate used in the synthesis of L-3-Phosphoglyceric Acid 13C3 (P358007), which is …

• Formula: C₃C₈H₁₃NO₅
• Color and Shape: Neat
• Molecular weight: 242.20258

N-Carboxybenzyl-L-serine

CAS: 1145-80-8

Applications Building block in peptide synthesis. References Pansare, S. V.; Org. Synth. 70, 10(1992)

• Formula: C₁₁H₁₃NO₅
• Color and Shape: Neat
• Molecular weight: 239.22

N-Cbz-L-serine

CAS: 1145-80-8

Please enquire for more information about N-Cbz-L-serine including the price, delivery time and more detailed …

• Formula: C₁₁H₁₃NO₅
• Purity: Min. 95%
• Color and Shape: White/Off-White Solid
• Molecular weight: 239.22 g/mol