CAS 114528-81-3

Benzeneacetamide, 3,4-dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]-, hydrochloride (1:1)

Description:

Benzeneacetamide, 3,4-dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]-, hydrochloride (1:1), with CAS number 114528-81-3, is a chemical compound characterized by its complex structure, which includes a benzeneacetamide moiety substituted with dichloro groups and a pyrrolidinyl-cyclohexyl side chain. This compound is typically classified as a pharmaceutical agent, potentially exhibiting psychoactive properties due to its structural similarity to other compounds that interact with the central nervous system. The presence of the hydrochloride salt form indicates enhanced solubility in water, which is often advantageous for drug formulation and delivery. The stereochemistry of the cyclohexyl group suggests specific spatial arrangements that may influence the compound's biological activity and receptor interactions. As with many compounds of this nature, safety and toxicity profiles would need to be evaluated through rigorous testing, and its use would be subject to regulatory oversight. Overall, this compound represents a significant interest in medicinal chemistry, particularly in the development of therapeutics targeting neurological conditions.

Formula: C₁₉H₂₆Cl₂N₂O·ClH

InChI: InChI=1S/C19H26Cl2N2O.ClH/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23;/h8-9,12,17-18H,2-7,10-11,13H2,1H3;1H/t17-,18-;/m1./s1

InChI key: InChIKey=KGMMGVIYOHGOKQ-JAXOOIEVSA-N

SMILES: N(C(CC1=CC(Cl)=C(Cl)C=C1)=O)(C)[C@H]2[C@@H](CCCC2)N3CCCC3.Cl

Synonyms:

• Benzeneacetamide, 3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-, monohydrochloride, (1R-trans)-
• Benzeneacetamide, 3,4-dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]-, hydrochloride (1:1)

(+)-U-50488 Hydrochloride

Controlled Product

CAS: 114528-81-3

(+)-U-50488 hydrochloride is a synthetic opioid analgesic, which was developed to be a potent and selective agonist at the κ-opioid receptor. The optical isomer of this drug has shown to be a more potent analgesic than the racemic mixture. This drug has been shown to produce an anti-nociceptive effect in mice with arthritis by inhibiting the release of glutamate, leading to an increased release of GABA in the spinal cord. (+)-U-50488 hydrochloride has been shown to have an antidepressant effect when used as a treatment for major depressive disorder. This drug also has a strong sedative effect and can cause respiratory depression, constipation, and nausea.

Formula: C₁₉H₂₇Cl₃N₂O

Purity: Min. 95%

Molecular weight: 405.8 g/mol

Ref: 3D-PEA52881