CAS 114547-31-8

galanin rat

Description:

Galanin rat, identified by its CAS number 114547-31-8, is a neuropeptide that plays a significant role in various physiological processes within the rat's body. It is a member of the galanin family of peptides, which are known for their involvement in neurotransmission and modulation of various functions such as pain perception, appetite regulation, and circadian rhythms. Galanin rat is characterized by its ability to bind to specific galanin receptors, which are G-protein-coupled receptors that mediate its biological effects. This peptide is primarily expressed in the central nervous system and peripheral tissues, influencing neuronal signaling and potentially impacting mood and behavior. Research into galanin and its receptors has implications for understanding various neurological disorders and developing therapeutic strategies. Its stability, solubility, and biological activity make it a subject of interest in pharmacological studies, particularly in the context of neurobiology and endocrinology.

Formula: C₁₄₁H₂₁₁N₄₃O₄₁

Synonyms:

• H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-His-Gly-Leu-Thr-NH2
• Galanin (rat)
• Galanin, Rat

Galanin (mouse, rat)

CAS: 114547-31-8

The isolation and characterization of cDNAs encoding rat galanin and its precursor peptide reveal that rat galanin is synthesized initially as part of a 124-amino acid precursor that includes a signal peptide, galanin, and a 60-amino acid galanin mRNA-associated peptide. The neuropeptide galanin shows multiple inhibitory actions on neurotransmission and memory. In Alzheimer’s disease, increased galanin-containing fibers hyperinnervate cholinergic neurons within the basal forebrain in association with a decline in cognition.

Formula: C₁₄₁H₂₁₁N₄₃O₄₁

Purity: ≥98%

Color and Shape: White

Molecular weight: 3164.49

Ref: 01-4030645

Galanin (1-29)(rat, mouse)

CAS: 114547-31-8

Non-selective galanin agonist; Ki: GAL1-0.98, GAL2-1.48, GAL3-1.47 nM. Anticonvulsant, stops full seizures in rats.

Formula: C₁₄₁H₂₁₁N₄₃O₄₁

Purity: 98%

Color and Shape: White Lyophilized Powder

Molecular weight: 3164.499

Ref: TM-TP2028

Galanin (Rat)

CAS: 114547-31-8

Galanin is a peptide that belongs to the family of neuropeptides and is found in the endocrine system, the central and peripheral nervous systems. It has been shown to inhibit the release of acetylcholine in the central nervous system and interestingly in Alzheimer’s disease patients, hyperinervation of galanin fibres has been found. Galanin is also known to have a variety of physiological effects including inhibition of insulin release, stimulation of prolactin and growth hormone secretion and it also plays a role in feeding, mood, cognition, neuroendocrine regulation and affects gastrointestinal motility. Galanin asserts its effects through associated with G-protein coupled receptors. This product is available as a 0.5mg vial.

Formula: C₁₄₁H₂₁₁N₄₃O₄₁

Purity: Min. 95%

Molecular weight: 3,164.5 g/mol

Ref: 3D-PGA-4244-V

Galanin (mouse, rat)

CAS: 114547-31-8

Structure/Function: mouse, rat

Formula: C₁₄₁H₂₁₁N₄₃O₄₁

Purity: Min. 95%

Molecular weight: 3,164.45 g/mol

Ref: 3D-FG110108