CAS 1146-99-2

clorindione

Description:

Clorindione, with the CAS number 1146-99-2, is a synthetic organic compound classified as a coumarin derivative. It is primarily known for its use as an anticoagulant and has applications in the field of medicine, particularly in the management of thromboembolic disorders. The compound exhibits a yellow crystalline appearance and is soluble in organic solvents, while its solubility in water is limited. Clorindione functions by inhibiting vitamin K epoxide reductase, which is crucial for the synthesis of certain clotting factors in the liver, thereby affecting the coagulation cascade. Its pharmacokinetics include oral bioavailability, and it is metabolized in the liver, with a variable half-life depending on individual patient factors. As with many anticoagulants, careful monitoring of blood coagulation parameters is essential during its use to prevent adverse effects such as bleeding. Overall, clorindione represents an important therapeutic agent in anticoagulation therapy, although its use may be limited by potential side effects and interactions with other medications.

Formula: C₁₅H₉ClO₂

InChI: InChI=1/C15H9ClO2/c16-10-7-5-9(6-8-10)13-14(17)11-3-1-2-4-12(11)15(13)18/h1-8,17H

InChI key: InChIKey=NJDUWAXIURWWLN-UHFFFAOYSA-N

SMILES: O=C1C(C(=O)C=2C1=CC=CC2)C3=CC=C(Cl)C=C3

Synonyms:

• 1,3-Indandione, 2-(p-chlorophenyl)-
• 1H-Indene-1,3(2H)-dione, 2-(4-chlorophenyl)-
• 2-(4-Chloro-phenyl)-indane-1,3-dione
• 2-(4-Chlorofenil)-1,3-indandione
• 2-(4-Chlorofenil)-1,3-indandione [Italian]
• 2-(4-Chlorophenyl)-1,3-indandione
• 2-(4-Chlorophenyl)-1H-indene-1,3(2H)-dione
• 2-(4-Chlorophenyl)-2,3-dihydro-1H-indene-1,3-dione
• 2-(4-Chlorophenyl)indan-1,3-dione
• 2-(4-Chlorophenyl)indene-1,3-dione
• 2-(4-chlorophenyl)-3-hydroxy-1H-inden-1-one
• 2-(p-Chlorophenyl)-1,3-indandione
• 2-(p-Chlorophenyl)indan-1,3-dione
• Brn 2052412
• Chlophenadione
• Chlor-athrombon
• Chlorathrombon
• Chlorindion
• Chlorindione
• Chlorindionum
• Chlorphenadione
• Chlorphenindione
• Ci-Pid
• Clorindiona
• Clorindiona [INN-Spanish]
• Clorindione [INN:BAN]
• Clorindionum
• Clorindionum [INN-Latin]
• Cumachlor
• G 25766
• Indalitan
• Indaliton
• M.G. 2552
• Mg 2552
• Unii-541C7Ws64R
• Clorindione
• g25766
• 2-(4'-CHLOROPHENY)LINDAN-1,3-DIONE
• 2-(4-CHLOROPHENYL)-1,3-INDANEDIONE, 97%
• G 25766,inhibit,G25766,Inhibitor,Chlorindione
• 2-(4-CHLOROPHENYL)INDANE-1,3-DIONE
• 2-(4-Chloropheny)indane-1,3-dione
• 2-(p-chlorophenyl)-3-indandione
• Clophenadione

1H-Indene-1,3(2H)-dione, 2-(4-chlorophenyl)-

CAS: 1146-99-2

Formula: C₁₅H₉ClO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 256.6838

Ref: IN-DA000ESP

Chlorindione

CAS: 1146-99-2

Chlorindione (chlophenadione) is a vitamin K antagonist, a potent anticoagulant compound.

Formula: C₁₅H₉ClO₂

Purity: 97.23% - 99.67%

Color and Shape: Solid

Molecular weight: 256.68

Ref: TM-T0360

2-(4'-Chloropheny)lindan-1,3-dione

CAS: 1146-99-2

2-(4'-Chloropheny)lindan-1,3-dione

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 256.68g/mol

Ref: 54-OR0282

Chlorindione

CAS: 1146-99-2

Chlorindione

Purity: ≥95%

Molecular weight: 256.68g/mol

Ref: 54-BUP14794

Clorindione

Controlled Product

CAS: 1146-99-2

Formula: C₁₅H₉ClO₂

Color and Shape: Neat

Molecular weight: 256.68

Ref: 04-C11687400

Clorindione

Controlled Product

CAS: 1146-99-2

Formula: C₁₅H₉ClO₂

Color and Shape: Neat

Molecular weight: 256.68

Ref: 86-MM3020.00

2-(4-Chlorophenyl)-1,3-indanedione

CAS: 1146-99-2

2-(4-Chlorophenyl)-1,3-indanedione is an analog of the nucleotide adenine. It is a fatty acid that can be synthesized from the fatty acid thioester. 2-(4-Chlorophenyl)-1,3-indanedione has been shown to have potent anti-inflammatory effects in animal models of inflammatory diseases. It also inhibits protein synthesis in bacteria and viruses by binding to proteins required for protein synthesis. This compound has also been shown to be toxic in animals at higher doses. The symptoms include myocarditis, cardiomyopathy, and arrhythmia.

Formula: C₁₅H₉ClO₂

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 256.68 g/mol

Ref: 3D-FC170050