CAS 114606-56-3

SDZ MKS 492

Description:

SDZ MKS 492, with the CAS number 114606-56-3, is a chemical compound that belongs to the class of sulfonamide antibiotics. It is primarily characterized by its ability to inhibit bacterial growth by interfering with the synthesis of folic acid, which is essential for bacterial cell metabolism and reproduction. This compound exhibits a broad spectrum of antibacterial activity, making it effective against various Gram-positive and Gram-negative bacteria. In terms of physical properties, SDZ MKS 492 is typically a solid at room temperature, with solubility in polar solvents. Its pharmacological profile suggests potential applications in treating infections, although specific therapeutic uses may vary. As with many sulfonamides, it may also be associated with certain side effects, including allergic reactions in sensitive individuals. Overall, SDZ MKS 492 represents a significant compound in the field of medicinal chemistry, particularly in the development of antimicrobial agents.

Formula: C₂₀H₂₇N₅O₆

InChI: InChI=1/C20H27N5O6/c1-23-17-16(18(27)24(2)20(23)28)25(8-9-29-3)19(22-17)21-13(11-26)12-6-7-14(30-4)15(10-12)31-5/h6-7,10,13,26H,8-9,11H2,1-5H3,(H,21,22)/t13-/m0/s1

SMILES: Cn1c2c(c(=O)n(C)c1=O)n(CCOC)c(=N[C@@H](CO)c1ccc(c(c1)OC)OC)[nH]2

Synonyms:

• (8-(1-(3,4-Dimethoxyphenyl)-2-hydroxyethyl)amino)-3,7-dihydro-7-(2-methoxyethyl)-1,3-dimethyl-1H-purine-2,6-dione
• Mks 492
• 1H-Purine-2,6-dione, 8-((1-(3,4-dimethoxyphenyl)-2-hydroxyethyl)amino)-3,7-dihydro-7-(2-methoxyethyl)-1,3-dimethyl-, (R)-
• 8-{[(1R)-1-(3,4-dimethoxyphenyl)-2-hydroxyethyl]amino}-7-(2-methoxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione

1H-Purine-2,6-dione, 8-[[(1R)-1-(3,4-dimethoxyphenyl)-2-hydroxyethyl]amino]-3,7-dihydro-7-(2-methoxyethyl)-1,3-dimethyl-

CAS: 114606-56-3

Formula: C₂₀H₂₇N₅O₆

Purity: 98.07%

Molecular weight: 433.4583

Ref: IN-DA000ESA

SDZ-MKS 492

Controlled Product

CAS: 114606-56-3

SDZ-MKS 492 is a drug that has been approved for the treatment of asthma in animals. It acts as a selective inhibitor of cyclic nucleotide phosphodiesterase (PDE) 3, which blocks cAMP and cGMP degradation. SDZ-MKS 492 has been shown to be effective in animal models of inflammatory bowel disease, cancer, and asthma. It also has bronchodilatory effects and may act as an anti-inflammatory agent by inhibition of cyclooxygenase activity.

Formula: C₂₀H₂₇N₅O₆

Purity: Min. 95%

Molecular weight: 433.5 g/mol

Ref: 3D-PEA60656

SDZ-MKS 492

CAS: 114606-56-3

SDZ-MKS 492 is a selective type III isozyme cyclic nucleotide phosphodiesterase inhibitor.

Formula: C₂₀H₂₇N₅O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 433.46

Ref: TM-T12873