CAS 114694-12-1

(5Z,7E)-(1S,3R)-1,3-Bis[tert-butyl(dimethylsilyl)oxy]-22-hydroxy-23,24-dinor-9,10-secochola-5,7,10(19)-triene

Controlled Product

CAS: 114694-12-1

Applications (5Z,7E)-(1S,3R)-1,3-Bis[tert-butyl(dimethylsilyl)oxy]-22-hydroxy-23,24-dinor-9,10-secochola-5,7,10(19)-triene is an intermediate in synthesizing ZK 159222 (Z485800), a vitamin D receptor antagonist. It is a derivative of Vitamin D3 (V676045).
References Mizwicki, M., et al.: J. Bio. Chem., 284, 36292 (2009); Ochiai, E., et al.: Mol. Endocrinol., 19, 1147 (2005)

Formula: C₃₄H₆₂O₃Si₂

Color and Shape: Neat

Molecular weight: 575.03

Ref: TR-B413020