CAS 1146967-62-5

[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-d9-[(4-nitrophenyl)sulfonyl]amino]\npropyl]carbamic Acid tert-Butyl Ester

Description:

The chemical substance known as [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-d9-[(4-nitrophenyl)sulfonyl]amino]propyl]carbamic Acid tert-Butyl Ester, with the CAS number 1146967-62-5, is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a benzyl group, a hydroxy group, and a tert-butyl ester, indicating its potential solubility in organic solvents and its reactivity in various chemical reactions. The presence of the isobutyl-d9 moiety suggests isotopic labeling, which can be useful in tracing studies or metabolic investigations. Additionally, the 4-nitrophenyl sulfonyl group indicates that this compound may have applications in medicinal chemistry, possibly as a prodrug or in the development of pharmaceuticals due to its ability to interact with biological targets. The stereochemical configuration (1S,2R) implies specific spatial arrangements that can influence the compound's biological activity and interactions. Overall, this compound's unique structure and functional groups make it a subject of interest in chemical research and development.

Formula: C₂₅H₃₅N₃O₇S

Synonyms:

• [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-d9-[(4-nitrophenyl)sulfonyl]amino]\npropyl]carbamic Acid tert-Butyl Ester

[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-d9-[(4-nitrophenyl)sulfonyl]amino]propyl]carbamic Acid tert-Butyl Ester

Controlled Product

CAS: 1146967-62-5

Applications An intermediate in the synthesis of labelled Amprenavir, a selective HIV protease inhibitor.
References Dorsey, B., et al.: J. Med. Chem., 37, 3443 (1994), Gong, Y., et al.: Antimicrob. Agents Chemother., 44, 2319 (2000), Maeda, K., et al.: J. Biol. Chem., 276, 35194 (2001),

Formula: C₂₅H₂₆D₉N₃O₇S

Color and Shape: Neat

Molecular weight: 530.68

Ref: TR-B279072