CAS 1146977-93-6

Atorvastatin Ethyl Ester (ethyl (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate)

CAS: 1146977-93-6

Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoi

Formula: C₃₅H₃₉FN₂O₅

Color and Shape: White Off-White Solid

Molecular weight: 586.2843

Ref: 45-1A00010

Atorvastatin EP Impurity M (Atorvastatin Ethyl Ester)

CAS: 1146977-93-6

Formula: C₃₅H₃₉FN₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 586.70

Ref: 4Z-A-1222

Atorvastatin Ethyl Ester

Controlled Product

CAS: 1146977-93-6

Formula: C₃₅H₃₉FN₂O₅

Color and Shape: Neat

Molecular weight: 586.69

Ref: 86-MM0400.30

Atorvastatin EP Impurity M

CAS: 1146977-93-6

Formula: C₃₅H₃₉FN₂O₅

Molecular weight: 586.7

Ref: ST-EA-CP-A32013

Atorvastatin Ethyl Ester

Controlled Product

CAS: 1146977-93-6

Applications Atorvastatin (A791750) impurity.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996);

Formula: C₃₅H₃₉FN₂O₅

Color and Shape: Off White Solid

Molecular weight: 586.69

Ref: TR-A791810

Atorvastatin ethyl ester

CAS: 1146977-93-6

Atorvastatin ethyl ester is a prodrug of atorvastatin that is used for the treatment of hypercholesterolemia. It inhibits HMG-CoA reductase, which reduces cholesterol production in the liver. The permeation rate of atorvastatin ethyl ester is increased by coadministration with c1-c10 fatty acids, which can be achieved by taking it with food. Atorvastatin ethyl ester has been shown to have antithrombotic and anti-inflammatory effects, which are due to its inhibition of the synthesis of thromboxane A2 and prostaglandin E2. Atorvastatin also inhibits protein synthesis in some cells, such as hepatocytes and neutrophils, but not in others such as fibroblasts or platelets. This may be related to the expression of an enzyme called cytosolic phospholipase A2 (cPLA2).

Formula: C₃₅H₃₉FN₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 586.69 g/mol

Ref: 3D-FA165519

Atorvastatin ethyl ester

CAS: 1146977-93-6

Atorvastatin ethyl ester, a derivative of Atorvastatin, exhibits potent inhibition of 9-cis-RA-induced Gal4 reporter activity.

Formula: C₃₅H₃₉FN₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 586.69

Ref: TM-T10403