CAS 114745-26-5

5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine

Description:

5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine is a modified nucleoside that features several distinctive chemical characteristics. It is a derivative of guanosine, which is one of the four primary nucleosides that make up RNA. The presence of a 5'-dimethoxytrityl (DMT) group indicates that this compound is likely used in oligonucleotide synthesis, as the DMT group serves as a protective group for the 5' hydroxyl. The N2-isobutyryl modification introduces an acyl group at the nitrogen position, which can influence the nucleoside's reactivity and stability. Additionally, the 2'-O-methyl modification enhances the compound's resistance to enzymatic degradation, making it more suitable for therapeutic applications. Overall, this compound is characterized by its structural complexity, which allows for specific interactions in biochemical processes, and its potential utility in research and pharmaceutical development, particularly in the context of RNA-based technologies.

Synonyms:

• DMT-2'-OMe-ibu-G
• 5'-O-DMT-N2-Isobutyryl-2'-O-Methyl-Guanosine

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine, 98%

CAS: 114745-26-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₃₆H₃₉N₅O₈

Purity: 98%

Molecular weight: 669.72

Ref: 02-J65583

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-

CAS: 114745-26-5

Formula: C₃₆H₃₉N₅O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 669.7236

Ref: IN-DA000F4X

5''-O-DMT-N2-isobutyryl-2''-O-methylguanosine

CAS: 114745-26-5

Formula: C₃₆H₃₉N₅O₈

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 669.72

Ref: 7W-GN3279

5’-​O-​[Bis(4-​Methoxyphenyl)​Phenylmethyl]​-​2’-​O-​Methyl-​N-​(2-​Methyl-​1-​Oxopropyl)​Guanosine

CAS: 114745-26-5

5’-​O-​[Bis(4-​Methoxyphenyl)​Phenylmethyl]​-​2’-​O-​Methyl-​N-​(2-​Methyl-​1-​Oxopropyl)​Guanosine

Purity: 99%

Molecular weight: 669.72g/mol

Ref: 54-OR1028848

5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine

CAS: 114745-26-5

5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine is a nucleoside that has been synthesized using an oxime opening of the 5' position and a methylation at the 2' position. It has been shown to have an affinity for tissues in a chemotactic assay. The compound is minimised to remove non-specific binding sites, avoiding false positives on the checklist. This molecule has been analysed with fluorescence spectroscopy and microscopy techniques, which revealed that it is distributed in tissues as well as being found in dragonflies. It was also shown to be transduced by muscle cells and geochemically detected in limestone from China.

Formula: C₃₆H₃₉N₅O₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 669.74 g/mol

Ref: 3D-ND03004

5′-​O-​[Bis(4-​methoxyphenyl)phenylmethyl]​-2′-​O-methyl-​N-(2-​methyl-​1-​oxopropyl)guanosine

CAS: 114745-26-5

Purity: 98%

Molecular weight: 669.735

Ref: 10-F988000

5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine

CAS: 114745-26-5

5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside synthesized through oxime ring-opening at the 5' position and methylation at the 2' position. In chemotaxis assays, 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine demonstrates tissue affinity.

Formula: C₃₆H₃₉N₅O₈

Color and Shape: Solid

Molecular weight: 669.724

Ref: TM-T206273