CAS 114748-70-8

7-Deaza-2',3'-Dideoxy-7-Iodo-Adenosine

Description:

7-Deaza-2',3'-Dideoxy-7-Iodo-Adenosine is a modified nucleoside analog of adenosine, characterized by the substitution of a nitrogen atom in the purine ring, which enhances its stability and alters its biological activity. The presence of the iodine atom at the 7-position contributes to its unique properties, potentially influencing its interaction with nucleic acid structures and enzymes. This compound is typically used in biochemical research and drug development, particularly in studies related to antiviral and anticancer therapies, due to its ability to mimic natural nucleosides while exhibiting altered pharmacological profiles. Its structural modifications can affect its solubility, binding affinity, and metabolic stability, making it a valuable tool in the exploration of nucleoside functions and mechanisms. As with many nucleoside analogs, the specific characteristics, such as solubility and reactivity, can vary based on the surrounding conditions and the presence of other chemical entities. Overall, 7-Deaza-2',3'-Dideoxy-7-Iodo-Adenosine represents an important compound in the field of medicinal chemistry and molecular biology.

Formula: C₁₁H₁₃IN₄O₂

Synonyms:

• 7-Deaza-2',3'-Dideoxy-7-Iodo-Adenosine
• (2S,5R)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydro-2-furanmethanol
• ((2S,5R)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-2-yl)methanol
• 7-I-7-Deaza-ddA
• 2-Furanmethanol, 5-(4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydro-, (2S,5R)-
• 7-Deaza-2',3'-Dideoxy-7-Iodo-D-Adenosine
• 2-Furanmethanol, 5-(4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydro-, (2S,5R)-7-Deaza-2', 3'-dideoxy-7-iodoadenosine
• 7-Deaza-7-Iodo-2',3'-dideoxyadenosine
• 7-Deaza-7-I-ddA

7-Iodo-2',3'-dideoxy-7-deazaadenosine

CAS: 114748-70-8

Formula: C₁₁H₁₃IN₄O₂

Purity: 98%

Molecular weight: 360.1510

Ref: IN-DA000F5M

((2S,5R)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-2-yl)methanol

CAS: 114748-70-8

((2S,5R)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-2-yl)methanol

Purity: 98%

Molecular weight: 360.16g/mol

Ref: 54-OR1073812

7-Iodo-2′,3′-dideoxy-7-deazaadenosine

CAS: 114748-70-8

Purity: 98%

Molecular weight: 360.155

Ref: 10-F983654

7-Deaza-2',3'-dideoxy-7-iodoadenosine

CAS: 114748-70-8

7-Deaza-2',3'-dideoxy-7-iodoadenosine is a nucleoside analogue that is used as an antiviral, anticancer, and antifungal agent. It is a modified form of adenosine which inhibits viral replication by inhibiting the activity of reverse transcriptase. 7-Deaza-2',3'-dideoxy-7-iodoadenosine has also been shown to inhibit DNA synthesis in cells by blocking the incorporation of dCTP into DNA. This nucleoside analogue has shown potential for use as an activator in phosphoramidite chemistry and as a deoxyribonucleoside in oligonucleotide synthesis.

Formula: C₁₁H₁₃IN₄O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 360.15 g/mol

Ref: 3D-ND44800

7-Iodo-2',3'-dideoxy-7-deazaadenosine

CAS: 114748-70-8

7-Iodo-2',3'-dideoxy-7-deazaadenosine is a dideoxynucleoside utilized in DNA synthesis and sequencing reactions.

Formula: C₁₁H₁₃IN₄O₂

Color and Shape: Solid

Molecular weight: 360.155

Ref: TM-T38533