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CAS 1147894-98-1

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4-Fluoro-3,5-diMethylphenylboronic acid, pinacol ester

Description:
4-Fluoro-3,5-dimethylphenylboronic acid, pinacol ester, is an organoboron compound characterized by the presence of a boronic acid functional group esterified with pinacol. This compound features a phenyl ring substituted with both a fluorine atom and two methyl groups, contributing to its unique reactivity and properties. The boronic acid moiety is known for its ability to form reversible covalent bonds with diols, making it valuable in various applications, including organic synthesis and medicinal chemistry. The presence of the fluorine atom can enhance the compound's lipophilicity and influence its biological activity. Additionally, the methyl groups can affect the steric hindrance and electronic properties of the molecule. This compound is typically used in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is pivotal in the formation of carbon-carbon bonds. Overall, 4-Fluoro-3,5-dimethylphenylboronic acid, pinacol ester, is a versatile building block in synthetic organic chemistry, with potential applications in drug development and materials science.
Formula:C14H20BFO2
Synonyms:
  • 4-Fluoro-3,5-diMethylphenylboronic acid, pinacol ester
  • 2-(4-Fluoro-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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