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CAS 114873-37-9

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DO3A

Description:
DO3A, or 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid, is a polyaminocarboxylic acid that serves as a chelating agent, particularly for metal ions. It features a cyclic structure with four nitrogen atoms and three carboxylic acid groups, which allows it to effectively bind to various metal ions, making it useful in applications such as radiopharmaceuticals and MRI contrast agents. The compound is known for its high stability and selectivity towards certain metal ions, including lanthanides and actinides. DO3A is often utilized in the development of imaging agents due to its ability to form stable complexes, which enhances the visibility of tissues in medical imaging. Additionally, its solubility in water and biocompatibility make it suitable for biological applications. The compound's unique structure and properties contribute to its significance in both research and clinical settings, particularly in the fields of medicinal chemistry and nuclear medicine.
Synonyms:
  • 1,4,7,10-Tetraazacyclododecaan-1,4,7-Triyltriazijnzuur
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