CAS 1149-23-1

Hantzsch ester

Description:

Hantzsch ester, known chemically as 1,3-dimethyl-4-(2,6-dimethylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate, is a synthetic compound primarily used in organic chemistry as a versatile building block for various reactions, particularly in the synthesis of biologically active molecules. It is characterized by its dihydropyridine structure, which features a fused ring system that contributes to its reactivity. The compound is typically a yellow to orange solid at room temperature and is soluble in organic solvents such as ethanol and dichloromethane. Hantzsch ester is notable for its role in the Hantzsch reaction, where it is formed through the condensation of aldehydes, ammonia, and β-keto esters, leading to the production of dihydropyridines. This compound is also recognized for its ability to act as a reducing agent in various chemical transformations, making it valuable in synthetic organic chemistry. Its stability and reactivity make it a useful intermediate in the development of pharmaceuticals and agrochemicals.

Formula: C₁₃H₁₉NO₄

InChI: InChI=1/C13H19NO4/c1-5-17-12(15)10-7-11(13(16)18-6-2)9(4)14-8(10)3/h14H,5-7H2,1-4H3

InChI key: InChIKey=LJXTYJXBORAIHX-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1CC(C(OCC)=O)=C(C)NC1C

Synonyms:

• 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester
• 1,4-Dihydro-3,5-dicarboxylic acid diethyl ester-2,6-dimethylpyridine
• 2,6-Dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester
• 2,6-Dimethyl-3,5-di(carboethoxy)-1,4-dihydropyridine
• 2,6-Dimethyl-3,5-dicarbethoxy-1,4-dihydropyridine
• 2,6-Dimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridin
• 2,6-Dimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridine
• 3,5-Bis(ethoxycarbonyl)-1,4-dihydro-2,6-dimethylpyridine
• 3,5-Bis(ethoxycarbonyl)-2,6-dimethyl-1,4-dihydropyridine
• 3,5-Dicarbethoxy-2,6-dimethyl-1,4-dihydropyridine
• 3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine
• 3,5-Diethoxycarbonyl-1,4-dihydro-2,6-dimethylpyridine
• 3,5-Diethoxycarbonyl-2,6-dimethyl-1,4-dihydropyridine
• 3,5-Diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-, diethyl ester
• Diethone
• Diethyl 2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate
• Diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
• Diludin
• Diludine
• Ethidine
• Hantzsch ester
• Hantzsch's dihydropyridine
• NSC 120573
• NSC 3344
• Rr 116
• 5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-diethylester
• rr116
• AURORA 4780
• etidin
• hantzschester
• DIETHYL 2,6-DIMETHYL-1,4-DIHYDRO-3,5-PYRIDINEDICARBOXYLATE
• diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate
• DIETHYL 2,6-DIMETHYL-1,4-DIHYDROPYRIDINEDICARBOXYLATE
• RARECHEM AQ NN 0171
• hantzsch’sdihydropyridine
• Dihydropyridinum

Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

CAS: 1149-23-1

Formula: C₁₃H₁₉NO₄

Purity: >98.0%(HPLC)(N)

Color and Shape: Light yellow to Yellow to Green powder to crystal

Molecular weight: 253.30

Ref: 3B-D3775

Diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate, 98%

CAS: 1149-23-1

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate is a hydrogen source in conjugate reduction and organocatalytic reductive amination. It is used as a hydrogen source in organocatalytic reductive amination and conjugate reduction. This Thermo Scientific Chemicals brand product was originall

Formula: C₁₃H₁₉NO₄

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, Pale yellow to yellow to green

Molecular weight: 253.30

Ref: 02-H55752

Diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS: 1149-23-1

Formula: C₁₃H₁₉NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 253.2943

Ref: IN-DA0034PZ

Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

CAS: 1149-23-1

Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Formula: C₁₃H₁₉NO₄

Purity: 95%

Color and Shape: faint yellow crystalline powder

Molecular weight: 253.29g/mol

Ref: 54-OR350125

3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine

CAS: 1149-23-1

Applications 3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine is a dihydropyridine derivative that have been tested for antimicrobial activities.
References Murthy, Y.L.. et al.: Bioorg. Med. Chem. Lett., 22, 6016 (2012); Vaitkuviene, A., et al.: Pharmacol. Rep., 58, 551 (2006);

Formula: C₁₃H₁₉NO₄

Color and Shape: Light Yellow To Light Green

Molecular weight: 253.29

Ref: TR-D431030

Diethyl 1,4-dihydro-2,6-dimethyl-3-5-pyridinedicarboxylate

CAS: 1149-23-1

Formula: C₁₃H₁₉NO₄

Purity: 98.0%

Color and Shape: Solid, Crystalline Powder or Powder

Molecular weight: 253.298

Ref: 10-F076860

Diethone

CAS: 1149-23-1

Diethone is a chemical compound that has been found to have a variety of biological effects. It has been shown to inhibit the activity of enzymes, such as phospholipase A2, cyclooxygenase-1 and -2, lipoxygenase-1 and -2, and glutathione S-transferases. In addition, diethone inhibits the synthesis of prostaglandins and leukotrienes. Diethone also has various physiological functions in humans. It is an eye irritant that can cause conjunctivitis and corneal damage if it comes into contact with the eye. Diethone also inhibits toll-like receptor (TLR) signaling in macrophages and myeloid cells, which may be due to its ability to inhibit NF-κβ activation. Diethone is also involved in metabolic disorders such as bowel disease or liver disease. This compound is metabolized by rat liver microsomes and produces a number of

Formula: C₁₃H₁₉NO₄

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 253.29 g/mol

Ref: 3D-FD00103