CAS 1149-99-1

illudin S

Description:

Illudin S is a naturally occurring sesquiterpene compound that is primarily derived from the fungus Omphalotus illudens, commonly known as the jack-o'-lantern mushroom. It is characterized by its complex molecular structure, which includes multiple rings and functional groups that contribute to its biological activity. Illudin S exhibits notable antifungal and cytotoxic properties, making it of interest in medicinal chemistry and pharmacology. The compound has been studied for its potential use in cancer treatment due to its ability to inhibit the growth of certain tumor cells. Additionally, illudin S is known for its instability and sensitivity to light and heat, which can affect its efficacy and handling. Its chemical formula reflects a specific arrangement of carbon, hydrogen, and oxygen atoms, contributing to its unique reactivity and interactions with biological systems. Overall, illudin S represents a fascinating example of a natural product with significant therapeutic potential, although further research is needed to fully understand its mechanisms of action and applications in medicine.

Formula: C₁₅H₂₀O₄

InChI: InChI=1/C15H20O4/c1-8-10-9(6-13(2,7-16)12(10)18)11(17)14(3,19)15(8)4-5-15/h6,12,16,18-19H,4-5,7H2,1-3H3/t12-,13+,14+/m1/s1

InChI key: InChIKey=DDLLIYKVDWPHJI-RDBSUJKOSA-N

SMILES: CC=1C2(CC2)[C@@](C)(O)C(=O)C=3C1[C@@H](O)[C@@](CO)(C)C3

Synonyms:

• (2'S,3'R,6'R)-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-2',3'-dihydrospiro[cyclopropane-1,5'-inden]-7'(6'H)-one
• (2′S,3′R,6′R)-2′,3′-Dihydro-3′,6′-dihydroxy-2′-(hydroxymethyl)-2′,4′,6′-trimethylspiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one
• 2',3'-Dihydro-2',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one
• Brn 2336420
• Ccris 3540
• Dr-15978
• Illudine S
• Lampterol
• Lunamycin
• Nsc 400979
• Nsc 626369
• Spiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-, (2'S-(2'alpha,3'beta,6'alpha))- (9CI)
• Spiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one, 2′,3′-dihydro-3′,6′-dihydroxy-2′-(hydroxymethyl)-2′,4′,6′-trimethyl-, (2′S,3′R,6′R)-
• Spiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one, 2′,3′-dihydro-3′,6′-dihydroxy-2′-(hydroxymethyl)-2′,4′,6′-trimethyl-, [2′S-(2′α,3′β,6′α)]-
• Sprio(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-, (2'S,3'R,6'R)-
• 4-08-00-02824 (Beilstein Handbook Reference)
• Illudin S
• CS-1385
• Illudin
• (2'S,3'R,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2'-hydroxymethyl-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one
• Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-, (2'S,3'R,6'R)-
• Illusin S

Illudin S

CAS: 1149-99-1

Illudin S

Purity: ≥98%

Molecular weight: 264.32g/mol

Ref: 54-BUP01227

Illudin S

CAS: 1149-99-1

Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.

Formula: C₁₅H₂₀O₄

Purity: 98.15%

Color and Shape: Solid

Molecular weight: 264.32

Ref: TM-T22857

llludin S

CAS: 1149-99-1

Illudin S is a sesquiterpene toxin, which is a naturally occurring compound isolated from several species of fungi belonging to the genus Omphalotus, such as Omphalotus olearius, commonly known as the Jack-o'-lantern mushroom. Its mode of action involves alkylating DNA, which leads to DNA cross-linking and subsequent inhibition of DNA synthesis. This mechanism renders it highly cytotoxic, as it can induce cell death by disrupting normal cellular replication processes.

Formula: C₁₅H₂₀O₄

Purity: Min. 95%

Molecular weight: 264.13616

Ref: 3D-FL178321