CAS 114915-14-9

Docetaxel intermediate

Description:

Docetaxel intermediate, identified by the CAS number 114915-14-9, is a crucial precursor in the synthesis of the chemotherapeutic agent docetaxel, which is used primarily in cancer treatment. This intermediate is characterized by its complex molecular structure, which includes multiple functional groups that facilitate its reactivity and transformation into the final drug. Typically, it exhibits properties such as moderate solubility in organic solvents and limited solubility in water, reflecting its hydrophobic nature. The compound is often handled with care due to its potential biological activity, and it may require specific storage conditions to maintain stability. In terms of safety, appropriate precautions should be taken to avoid exposure, as intermediates in pharmaceutical synthesis can pose health risks. Overall, docetaxel intermediate plays a vital role in the pharmaceutical industry, particularly in the development of effective cancer therapies.

Formula: C₄₉H₅₅Cl₆NO₁₈

InChI: InChI=1/C49H55Cl6NO18/c1-24-28(69-39(61)33(58)32(26-15-11-9-12-16-26)56-40(62)74-43(3,4)5)20-47(65)37(72-38(60)27-17-13-10-14-18-27)35-45(8,36(59)34(31(24)44(47,6)7)71-42(64)68-23-49(53,54)55)29(70-41(63)67-22-48(50,51)52)19-30-46(35,21-66-30)73-25(2)57/h9-18,28-30,32-35,37,58,65H,19-23H2,1-8H3,(H,56,62)/t28-,29-,30+,32-,33+,34+,35-,37-,45+,46-,47+/m0/s1

Synonyms:

• Intermediate For Docetaxel
• Intermediateiiifordocetaxel
• Intermediateofdocetaxel
• N-1 Step intermediate
• (aR,bS)-beta-[[(1,1-Dimethylethoxy)carbonyl]amino]-alpha-hydroxy-benzenepropanoic acid
• (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4,6-bis[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester
• (2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1-hydroxy-9-oxo-7,10-bis{[(2,2,2-trichloroethoxy)carbonyl]oxy}-5,20-epoxytax-11-en-2-yl benzoate
• 7,10-O-Ditroc docetaxel
• 7,10-Ditroc Docetaxel
• 7,10-di-Troc-Docetaxel

Benzenepropanoic acid,b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxy-,12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4,6-bis[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,[2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,1

CAS: 114915-14-9

Formula: C₄₉H₅₅Cl₆NO₁₈

Purity: 98%

Molecular weight: 1158.6749

Ref: IN-DA00HCX7

Docetaxel intermediate

CAS: 114915-14-9

Formula: C₄₉H₅₅Cl₆NO₁₈

Purity: 95%~99%

Molecular weight: 1158.67

Ref: BP-BP4224

7,10-O-Bis{[(2,2,2,-trichloroethyl)oxy]carbonyl} Docetaxel-d9

Controlled Product

CAS: 114915-14-9

Applications Labelled Docetaxel derivative as antitumor agent.
References Ojima, I., et al.: Bioorg. Med. Chem., 8, 1619 (2000),

Formula: C₄₉D₉H₄₆Cl₆NO₁₈

Color and Shape: Neat

Molecular weight: 1167.73

Ref: TR-B693542

7,10-Ditroc Docetaxel

CAS: 114915-14-9

Formula: C₄₉H₅₅Cl₆NO₁₈

Molecular weight: 1158.7

Ref: ST-EA-CP-D32048