CAS 1149705-71-4

XL-888

Description:

XL-888, with the CAS number 1149705-71-4, is a chemical compound that has been studied primarily for its potential applications in the field of oncology. It is classified as a small molecule inhibitor, specifically targeting certain kinases involved in cellular signaling pathways that regulate cell growth and survival. The compound exhibits properties that may contribute to its effectiveness in inhibiting tumor growth and proliferation. XL-888 has been evaluated in various preclinical studies, demonstrating its ability to interfere with the activity of specific proteins that are often overexpressed in cancer cells. Its mechanism of action typically involves the disruption of signaling cascades that are crucial for cancer cell survival. Additionally, the compound's pharmacokinetic profile, including absorption, distribution, metabolism, and excretion, is essential for determining its therapeutic potential and safety in clinical settings. As research continues, further insights into its efficacy and possible side effects will be critical for its development as a therapeutic agent.

1,4-Benzenedicarboxamide, N1-[(3-endo)-8-[5-(cyclopropylcarbonyl)-2-pyridinyl]-8-azabicyclo[3.2.1]oct-3-yl]-2-methyl-5-[[(1R)-1-methylpropyl]amino]-

CAS: 1149705-71-4

Formula: C₂₉H₃₇N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 503.6358

Ref: IN-DA000FIA

5-(((R)-Sec-Butyl)Amino)-N1-((3-Endo)-8-(5-(Cyclopropanecarbonyl)Pyridin-2-Yl)-8-Azabicyclo[3.2.1]Octan-3-Yl)-2-Methylterephthalamide

CAS: 1149705-71-4

5-(((R)-Sec-Butyl)Amino)-N1-((3-Endo)-8-(5-(Cyclopropanecarbonyl)Pyridin-2-Yl)-8-Azabicyclo[3.2.1]Octan-3-Yl)-2-Methylterephthalamide

Purity: 95%

Molecular weight: 503.64g/mol

Ref: 54-OR1024040

XL888

CAS: 1149705-71-4

XL888

Purity: ≥98%

Molecular weight: 503.64g/mol

Ref: 54-BUP05436

XL888

CAS: 1149705-71-4

XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.

Formula: C₂₉H₃₇N₅O₃

Purity: 99.18%

Color and Shape: Solid

Molecular weight: 503.64

Ref: TM-T6248

XL888

CAS: 1149705-71-4

XL888 is a selective and potent inhibitor of heat shock protein 90 (HSP90), which is a molecular chaperone involved in the proper folding, stability, and function of many client proteins, including those critical in cancer progression. Sourced from rigorous medicinal chemistry processes, XL888 is designed to bind to the ATP-binding site of HSP90, thereby inhibiting its chaperone activity. This inhibition leads to the degradation of client proteins that are essential for tumor growth and survival.

Formula: C₂₉H₃₇N₅O₃

Purity: Min. 95%

Molecular weight: 503.64 g/mol

Ref: 3D-ZVB70571