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CAS 114991-25-2

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4-Hydroxy Propofol 1-O-b-D-Glucuronide

Description:
4-Hydroxy Propofol 1-O-b-D-Glucuronide is a chemical compound that serves as a metabolite of propofol, a widely used anesthetic agent. This substance is characterized by the presence of a hydroxy group and a glucuronide moiety, which indicates that it has undergone conjugation, a common metabolic process that enhances the solubility of lipophilic compounds for excretion. The glucuronidation process typically occurs in the liver and is facilitated by UDP-glucuronosyltransferases. As a result, 4-Hydroxy Propofol 1-O-b-D-Glucuronide is more water-soluble than its parent compound, propofol, which aids in its elimination from the body. The compound is of interest in pharmacokinetics and toxicology, particularly in understanding the metabolism of propofol and its potential effects on patients. Its structure and properties may influence its biological activity and interactions within the body, making it relevant for research in anesthetic pharmacology and drug metabolism.
Formula:C18H26O8
InChI:InChI=1/C18H26O8/c1-7(2)10-5-9(19)6-11(8(3)4)15(10)25-18-14(22)12(20)13(21)16(26-18)17(23)24/h5-8,12-14,16,18-22H,1-4H3,(H,23,24)/t12-,13-,14-,16?,18+/m0/s1
Synonyms:
  • 4-Hydroxy-2,6-bis(1-methylethyl)phenyl b-D-Glucopyranosiduronic Acid
  • 4-Hydroxy Propofol 1-O--D-Glucuronide
  • 4-Hydroxy-2,6-bis(1-methylethyl)phenyl -D-Glucopyranosiduronic Acid
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