CAS 115-53-7
:sinomenine
Description:
Sinomenine is an alkaloid derived from the plant Sinomenium acutum, commonly used in traditional medicine, particularly in East Asia. It is characterized by its complex tetracyclic structure, which contributes to its pharmacological properties. Sinomenine exhibits anti-inflammatory, analgesic, and immunomodulatory effects, making it of interest in the treatment of conditions such as rheumatoid arthritis and other inflammatory diseases. The compound has a moderate solubility in water and is more soluble in organic solvents, which influences its bioavailability and therapeutic applications. Its mechanism of action involves modulation of various signaling pathways, including those related to pain and inflammation. Sinomenine's safety profile and potential side effects are still under investigation, but it is generally considered to have a favorable therapeutic index when used appropriately. As research continues, sinomenine may offer insights into new treatment modalities for chronic inflammatory conditions.
Formula:C19H23NO4
InChI:InChI=1/C19H23NO4/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9,12-13,22H,6-8,10H2,1-3H3/t12-,13+,19-/m1/s1
InChI key:InChIKey=INYYVPJSBIVGPH-QHRIQVFBSA-N
SMILES:OC1=C2[C@]34[C@@]([C@](CC2=CC=C1OC)(N(C)CC3)[H])(C=C(OC)C(=O)C4)[H]
Synonyms:- (9Alpha,13Alpha,14Alpha)-4-Hydroxy-3,7-Dimethoxy-17-Methyl-7,8-Didehydromorphinan-6-One
- (9alpha,13alpha,14alpha)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
- (9α,13α,14α)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
- 7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9-alpha,13-alpha,14-alpha-morphinan-6-one
- 9-alpha,13-alpha,14-alpha-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-
- 9α,13α,14α-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-
- Brn 0095280
- Ccris 1550
- Coculine
- Cucoline
- Kukoline
- Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, (9α,13α,14α)-
- Sabianine A
- Sinomenin
- Sinomenine
- 5-21-13-00516 (Beilstein Handbook Reference)
- SinoMenine (Cucoline)
- Sinomenine Standard
- Sinomenine, >=98%
- 9α,13α,14α-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-onehydrochloride
- SabiaineA
- 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9-alpha,13-alpha,14-alpha-mo
- Sinomenine CRS
- (9Alpha,13alpha,14alpha)-4-hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochlo
- y-17-methyl-
- Sinomenine std.
- rphinan-6-one
- Sinomenine hydrochlo
- Sinomenine/Sinomenine Hydrochloride
- SinoMenine (6CI,7CI)
- Sinomenine 0.3 mol chloroform of crystallization
- Sinomenine 115-53-7
- Sinomenine I
- (+)-SinoMenine N-oxide
- SINGLIROXBRUGHROSEFRUITP.E
- Sinomenine, 98%, from Caulis Sinomenii
- 9-alpha,13-alpha,14-alpha-morphinan-6-one,7,8-didehydro-4-hydroxy-3,7-dimethox
- Sinomenine USP/EP/BP
- Sinomenine，Coculine，Cucoline，Tuduranine
- SNM
- (4bR,8aS,9S)-4-hydroxy-3,7-dimethoxy-11-methyl-9,10-dihydro-5H-9,4b-(epiminoethano)phenanthren-6(8aH)-one
- Sinomenine hydrochorolide
- SINOMENINE(RG)
- (9alpha,13alpha,14alpha)-4-hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochloride
- See more synonyms
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Found 10 products.
SINOMENINE CRS
CAS:SINOMENINE CRSFormula:C19H23NO4Color and Shape:Needles. Cristalline. White. Powder.Molecular weight:329.3902Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, (9α,13α,14α)-
CAS:Formula:C19H23NO4Purity:%Color and Shape:SolidMolecular weight:329.3902Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purity:99.02% - 99.73%Color and Shape:White PowderMolecular weight:329.39Sinomenine
CAS:Controlled Product<p>Sinomenine is an alkaloid compound, which is extracted from the plant Sinomenium acutum. This perennial climbing vine is a member of the Menispermaceae family and is traditionally used in Chinese medicine. Sinomenine primarily exerts its effects by modulating the immune response and exhibiting anti-inflammatory properties. It achieves this through the inhibition of pro-inflammatory cytokines, such as TNF-α and IL-6, and by interfering with the activation of nuclear factor-kappa B (NF-κB), a key player in inflammatory pathways.</p>Formula:C19H23NO4Purity:Min. 95%Color and Shape:White PowderMolecular weight:329.39 g/mol
