CAS 115-53-7: sinomenine
Description:Sinomenine is an alkaloid derived from the plant Sinomenium acutum, commonly used in traditional medicine, particularly in East Asia. It is characterized by its complex tetracyclic structure, which contributes to its pharmacological properties. Sinomenine exhibits anti-inflammatory, analgesic, and immunomodulatory effects, making it of interest in the treatment of conditions such as rheumatoid arthritis and other inflammatory diseases. The compound has a moderate solubility in water and is more soluble in organic solvents, which influences its bioavailability and therapeutic applications. Its mechanism of action involves modulation of various signaling pathways, including those related to pain and inflammation. Sinomenine's safety profile and potential side effects are still under investigation, but it is generally considered to have a favorable therapeutic index when used appropriately. As research continues, sinomenine may offer insights into new treatment modalities for chronic inflammatory conditions.
Formula:C19H23NO4
InChI:InChI=1S/C19H23NO4/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9,12-13,22H,6-8,10H2,1-3H3/t12-,13+,19-/m1/s1
InChI key:InChIKey=INYYVPJSBIVGPH-QHRIQVFBSA-N
SMILES:O=C1C(OC)=CC2C3N(C)CCC2(C4=C(O)C(OC)=CC=C4C3)C1
- Synonyms:
- (9Alpha,13Alpha,14Alpha)-4-Hydroxy-3,7-Dimethoxy-17-Methyl-7,8-Didehydromorphinan-6-One
- (9alpha,13alpha,14alpha)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
- (9α,13α,14α)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
- 7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9-alpha,13-alpha,14-alpha-morphinan-6-one
- 9-alpha,13-alpha,14-alpha-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-
- 9α,13α,14α-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-
- Brn 0095280
- Ccris 1550
- Coculine
- Cucoline
- See more synonyms
- Kukoline
- Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, (9α,13α,14α)-
- Sabianine A
- Sinomenin
- Sinomenine
- 5-21-13-00516 (Beilstein Handbook Reference)
