CAS 115-61-7

Tachysterol

Description:

Tachysterol, with the CAS number 115-61-7, is a sterol compound that is a derivative of vitamin D2. It is characterized by its role as a metabolite in the vitamin D metabolic pathway, specifically as an intermediate in the conversion of ergosterol to vitamin D2 upon UV irradiation. Tachysterol is known for its ability to absorb ultraviolet light, which facilitates its conversion to more biologically active forms of vitamin D. The compound is typically a white to off-white crystalline solid and is soluble in organic solvents but has limited solubility in water. Its structure features a steroid nucleus with specific functional groups that contribute to its biological activity. Tachysterol is of interest in various fields, including biochemistry and pharmacology, due to its potential effects on calcium metabolism and bone health. However, it is less active than its more well-known counterparts, such as ergocalciferol (vitamin D2) and calcitriol (the active form of vitamin D).

Formula: C₂₈H₄₄O

InChI: InChI=1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h8-10,12-13,19-20,22,25-27,29H,7,11,14-18H2,1-6H3/b10-9+,13-12+/t20-,22+,25-,26+,27-,28+/m0/s1

InChI key: InChIKey=XQFJZHAVTPYDIQ-LETJEVNCSA-N

SMILES: C[C@@]12[C@](C(/C=C/C3=C(C)CC[C@H](O)C3)=CCC1)(CC[C@@]2([C@@H](/C=C/[C@@H](C(C)C)C)C)[H])[H]

Synonyms:

• (1S)-3-[(1E)-2-[(1R,3aR,7aR)-2,3,3a,6,7,7a-Hexahydro-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl]-1H-inden-4-yl]ethenyl]-4-methyl-3-cyclohexen-1-ol
• (6E,22E)-9,10-secoergosta-5(10),6,8,22-tetraen-3-ol
• 3-Cyclohexen-1-ol, 3-[(1E)-2-[(1R,3aR,7aR)-2,3,3a,6,7,7a-hexahydro-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl]-1H-inden-4-yl]ethenyl]-4-methyl-, (1S)-
• 9,10-Secoergosta-5(10),6,8,22-tetraen-3-ol, (3β,6E,22E)-
• Provitamin D
• Tachysterin₂
• Tachysterol
• Tachysterol₂

Ergocalciferol EP Impurity E (Tachysterol)

CAS: 115-61-7

Formula: C₂₈H₄₄O

Color and Shape: Off-White Solid

Molecular weight: 396.66

Ref: 4Z-V-038012

Tachysterol (>90%)

CAS: 115-61-7

Stability Light Sensitive, Temperature Sensitive
Applications Bioactive, synthetic vitamin D3 analog; exhibits antiproliferative effect on keratinocytes. Antipsoriatic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Matsunaga, T., et al.: J. Dermatol., 17, 135 (1990), Gerritsen, M.J.P., et al.: Br. J. Dermatol., 131, 57 (1994),

Formula: C₂₈H₄₄O

Purity: >90%

Color and Shape: Neat

Molecular weight: 396.65

Ref: TR-T004100

Tachysterol

CAS: 115-61-7

Tachysterol is a sterol derivative that serves as a vitamin D analog, primarily sourced from the photochemical isomerization of ergosterol or lumisterol. Tachysterol undergoes further conversion processes to become active vitamin D metabolites that play crucial roles in calcium and phosphorus homeostasis. Though not biologically active in its original form, tachysterol is a precursor in the metabolic pathway, with conversion into active forms such as calcitriol occurring in the body.

Formula: C₂₈H₄₄O

Purity: 90% Min

Color and Shape: Powder

Molecular weight: 396.65 g/mol

Ref: 3D-FT27986

Ergocalciferol EP Impurity E

CAS: 115-61-7

Formula: C₂₈H₄₄O

Molecular weight: 396.66

Ref: ST-EA-CP-E70005