CAS 1150-26-1

N-(4-Methoxyphenyl)-4-methylbenzenesulfonamide

Description:

N-(4-Methoxyphenyl)-4-methylbenzenesulfonamide, with the CAS number 1150-26-1, is an organic compound characterized by its sulfonamide functional group, which is known for its applications in medicinal chemistry, particularly as a scaffold in drug development. This compound features a sulfonamide moiety attached to a 4-methylbenzene ring and a 4-methoxyphenyl group, contributing to its potential biological activity. The presence of the methoxy group enhances its lipophilicity, which can influence its solubility and permeability in biological systems. Typically, sulfonamides exhibit antibacterial properties, and their derivatives are often explored for various therapeutic applications. The compound's molecular structure suggests it may engage in hydrogen bonding and other intermolecular interactions, which are crucial for its reactivity and interaction with biological targets. Additionally, its stability and reactivity can be influenced by the electronic effects of the substituents on the aromatic rings. Overall, N-(4-Methoxyphenyl)-4-methylbenzenesulfonamide represents a class of compounds with significant interest in pharmaceutical research.

Formula: C₁₄H₁₅NO₃S

InChI: InChI=1S/C14H15NO3S/c1-11-3-9-14(10-4-11)19(16,17)15-12-5-7-13(18-2)8-6-12/h3-10,15H,1-2H3

InChI key: InChIKey=GFPBLDMXBCYORT-UHFFFAOYSA-N

SMILES: S(NC1=CC=C(OC)C=C1)(=O)(=O)C2=CC=C(C)C=C2

Synonyms:

• Benzenesulfonamide, N-(4-methoxyphenyl)-4-methyl-
• N-(4-Methoxyphenyl)tosylamide
• 4′-Methoxy-4-methylbenzenesulfonanilide
• N-(4-Methoxyphenyl)-4-methylbenzenesulfonamide
• p-Toluenesulfon-p-anisidide