CAS 115007-34-6

Mycophenolate mofetil

Description:

Mycophenolate mofetil (MMF) is an immunosuppressive agent primarily used to prevent organ rejection in transplant patients and to treat autoimmune diseases. It is a prodrug that is converted in the body to mycophenolic acid, which inhibits the enzyme inosine monophosphate dehydrogenase (IMPDH). This inhibition selectively affects lymphocytes, thereby suppressing the proliferation of T and B cells and reducing the immune response. MMF is typically administered orally and is characterized by its moderate solubility in water and higher solubility in organic solvents. The substance has a molecular formula that reflects its complex structure, which includes a morpholino group and a carboxylic acid moiety. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations occurring within a few hours post-administration. Side effects may include gastrointestinal disturbances, increased risk of infections, and hematological abnormalities. Due to its immunosuppressive properties, careful monitoring is essential during treatment to mitigate potential complications.

Formula: C₂₃H₃₁NO₇

InChI: InChI=1/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3

InChI key: InChIKey=RTGDFNSFWBGLEC-SYZQJQIISA-N

SMILES: CC(=CCc1c(c2c(COC2=O)c(C)c1OC)O)CCC(=O)OCCN1CCOCC1

Synonyms:

• 2-(Morpholin-4-Yl)Ethyl 6-(4-Hydroxy-6-Methoxy-7-Methyl-3-Oxo-1,3-Dihydro-2-Benzofuran-5-Yl)-4-Methylhex-4-Enoate
• 2-Morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoate
• 2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
• 4-Hexenoic Acid,6-(1,3-Dihydro-4-Hydroxy-6-Methoxy-7-Methyl-3-Oxo-5-Isobenzofuranyl)-4-Methyl-,2-(4-Morpholinyl)Ethyl Ester
• 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)-
• 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (E)-
• 6-[(7-Hydroxy-5-Methoxy-4-Methyl-1-Oxo-3H-Isobenzofuran-6-Yl)]-4-Methyl-Hex-4-Enoic Acid 2-Morpholinoethyl Ester
• Linfonex
• MMF
• Macophenolate Mofetil
• Micoflavin
• Mofetil mycophenolate
• Myclausen
• Mycophenelate Mofetil
• Mycophenolate
• Mycophenolate Mofetil(MMF)
• MycophenolicAcid-2-(4-Morpholinyl)ethylEster
• Myfenax
• Rs 61443
• Suprimun

RS 61443

CAS: 115007-34-6

RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)

Formula: C₂₃H₃₁NO₇

Purity: 99.37% - 99.91%

Color and Shape: Solid

Molecular weight: 433.5

Ref: TM-T0245

Mycophenolate mofetil

CAS: 115007-34-6

Formula: C₂₃H₃₁NO₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 433.4947

Ref: IN-DA01FFZI

RS 61443

CAS: 115007-34-6

RS 61443

Purity: ≥98%

Molecular weight: 433.5g/mol

Ref: 54-BUP15052