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CAS 115044-75-2

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2-chloro-3'-deoxyadenosine

Description:
2-Chloro-3'-deoxyadenosine (CAS 115044-75-2) is a synthetic nucleoside analog of adenosine, characterized by the presence of a chlorine atom at the 2-position of the ribose sugar and a deoxy group at the 3' position. This modification alters its biological activity, making it of interest in medicinal chemistry, particularly in the context of antiviral and anticancer research. The compound exhibits properties that can interfere with nucleic acid synthesis, potentially leading to the inhibition of cell proliferation. It is typically soluble in polar solvents, and its structure allows for interactions with various biological targets, including enzymes involved in nucleotide metabolism. The compound's mechanism of action often involves incorporation into DNA or RNA, leading to chain termination or misincorporation during replication. As a result, 2-chloro-3'-deoxyadenosine has been studied for its therapeutic potential, especially in the treatment of certain viral infections and malignancies, although its use may be limited by toxicity and side effects associated with nucleoside analogs.
Formula:C10H12ClN5O3
InChI:InChI=1/C10H12ClN5O3/c11-10-14-7(12)6-8(15-10)16(3-13-6)9-5(18)1-4(2-17)19-9/h3-5,9,17-18H,1-2H2,(H2,12,14,15)/t4-,5+,9+/m0/s1
Synonyms:
  • 2-Cda
  • 3'-Deoxy-2-chloroadenosine
  • Adenosine, 2-chloro-3'-deoxy-
  • 2-Chloro-3'-deoxyadenosine
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