CAS 115075-59-7
:Ibuprofen glucuronide
Description:
Ibuprofen glucuronide is a metabolite of ibuprofen, a widely used nonsteroidal anti-inflammatory drug (NSAID). It is formed through the process of glucuronidation, where the ibuprofen molecule is conjugated with glucuronic acid, enhancing its solubility and facilitating excretion. This compound is typically characterized by its molecular formula, which reflects the addition of a glucuronic acid moiety to the ibuprofen structure. Ibuprofen glucuronide is generally less pharmacologically active than its parent compound, ibuprofen, but it plays a crucial role in the drug's metabolism and elimination from the body. Its presence in biological samples can be indicative of ibuprofen use and is often analyzed in pharmacokinetic studies. The compound is soluble in water due to its polar nature, which is a result of the glucuronidation process. Understanding the characteristics of ibuprofen glucuronide is essential for comprehending the metabolic pathways of ibuprofen and its overall pharmacological profile.
Formula:C19H26O8
InChI:InChI=1/C19H26O8/c1-9(2)8-11-4-6-12(7-5-11)10(3)18(25)27-19-15(22)13(20)14(21)16(26-19)17(23)24/h4-7,9-10,13-16,19-22H,8H2,1-3H3,(H,23,24)/t10?,13-,14-,15+,16-,19-/m0/s1
InChI key:InChIKey=ABOLXXZAJIAUGR-JPMMFUSZSA-N
SMILES:O(C(C(C)C1=CC=C(CC(C)C)C=C1)=O)[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O
Synonyms:- 1-O-{2-[4-(2-methylpropyl)phenyl]propanoyl}-beta-D-glucopyranuronic acid
- 1-[a-Methyl-4-(2-methylpropyl)benzeneacetate] -D-Glucopyranuronic Acid
- 1-[alpha-Methyl-4-(2-methylpropyl)benzeneacetate] -D-Glucopyranuronic acid
- Ibuprofen Acyl Glucuronide
- Ibuprofen Acyl--D-glucuronide
- Ibuprofen glucuronide
- Ibuprofen-β-<span class="text-smallcaps">D</span>-glucuronide
- β-<span class="text-smallcaps">D</span>-Glucopyranuronic acid, 1-[α-methyl-4-(2-methylpropyl)benzeneacetate]
- β-D-Glucopyranuronic acid, 1-[α-methyl-4-(2-methylpropyl)benzeneacetate]
- Ibuprofen-β-D-glucuronide
- 1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid
- (R,S)-Ibuprofen-acyl-beta-D-glucuronide min. 98%
- 1-[α-Methyl-4-(2-Methylpropyl)benzeneacetate] β-D-Glucopyranuronic Acid
- Ibuprofen Acyl-beta-D- Glucuronide
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.
Ibuprofen Acyl-b-D-glucuronide (mixture of diastereomers)
CAS:Formula:C19H26O8Color and Shape:SolidMolecular weight:382.4049Ibuprofen Acyl Glucuronide (Mixture of Diastereomers)
CAS:Formula:C19H26O8Color and Shape:White To Off-White SolidMolecular weight:382.41(R,S)-Ibuprofen-acyl-β-D-glucuronide
CAS:(R,S)-Ibuprofen-acyl-β-D-glucuronidePurity:>98%Color and Shape:CrystalsMolecular weight:382.40g/molIbuprofen Acyl-β-D-glucuronide (mixture of diastereomers)
CAS:<p>Stability Hygroscopic, Not stable in aqueous solutions.<br>Applications Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers) (cas# 115075-59-7) is a compound useful in organic synthesis.<br></p>Formula:C19H26O8Color and Shape:NeatMolecular weight:382.40Ibuprofen-d3 Acyl-β-D-glucuronide (mixture of diastereomers)
CAS:Controlled Product<p>Applications Ibuprofen-d3 Acyl-β-D-glucuronide (mixture of diastereomers) is a compound useful in organic synthesis.<br></p>Formula:C19D3H23O8Color and Shape:NeatMolecular weight:385.42Ibuprofen acyl-b-D-glucuronide
CAS:<p>Ibuprofen acyl-b-D-glucuronide is a biologically active molecule. It is metabolized in humans by first being hydrolyzed to ibuprofen and then glucuronidated. The enzyme that catalyzes this reaction is uridine 5'-diphosphate glucuronosyltransferase 1A1 (UGT1A1). Ibuprofen acyl-b-D-glucuronide has been shown to have an inhibitory effect on inflammation in vitro assays, such as the rat paw edema assay. This drug also has a reactive and chromatographic profile that allows it to be used in wastewater treatment.</p>Formula:C19H26O8Purity:Min. 95%Color and Shape:White PowderMolecular weight:382.4 g/mol
