CAS 115104-28-4

3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid

Description:

The chemical substance known as 3-[[[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid, with the CAS number 115104-28-4, is a complex organic compound characterized by its multi-functional structure. It features a quinoline moiety, which contributes to its potential biological activity, particularly in medicinal chemistry. The presence of a thioether and a carboxylic acid group suggests that it may exhibit both lipophilic and hydrophilic properties, influencing its solubility and reactivity. The dimethylamino group may enhance its interaction with biological targets, potentially affecting its pharmacological profile. This compound is likely to be of interest in research related to drug development, particularly in the context of targeting specific biological pathways or diseases. Its intricate structure indicates potential for diverse chemical reactivity, making it a candidate for further studies in synthetic organic chemistry and pharmacology.

Formula: C₂₆H₂₇ClN₂O₃S₂

InChI: InChI=1/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+

InChI key: InChIKey=AXUZQJFHDNNPFG-UXBLZVDNNA-N

SMILES: C(=C/C1=CC(C(SCCC(N(C)C)=O)SCCC(O)=O)=CC=C1)\C2=NC3=C(C=C2)C=CC(Cl)=C3

Synonyms:

• 3-[({3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl)sulfanyl]propanoic acid
• 3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic Acid Sodium Salt
• 3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid
• 3-{[(R)-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid
• L 660711
• L 660711, Sodium Salt
• Mk-571
• Mk-571 Na
• Mk-571 Sodium Salt
• Mk-571, Na Salt
• Propanoic acid, 3-[[[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-
• Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-, (E)-

Propanoic acid, 3-[[[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-

CAS: 115104-28-4

Formula: C₂₆H₂₇ClN₂O₃S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 515.0872

Ref: IN-DA000GAT

MK 571

CAS: 115104-28-4

MK 571

Purity: ≥98%

Molecular weight: 515.09g/mol

Ref: 54-BUP05737

MK 571

CAS: 115104-28-4

MK 571 (L660711) is an orally active antagonist of CysLT1 receptor.

Formula: C₂₆H₂₇ClN₂O₃S₂

Purity: 98.69% - 99.65%

Color and Shape: Solid

Molecular weight: 515.09

Ref: TM-T7841

MK-571

Controlled Product

CAS: 115104-28-4

Stability Hygroscopic
Applications A receptor antagonist for the treatment of respiratory diseases. Cysteinyl leukotriene receptor antagonist MK-571 alters bronchoalveolar lavage fluid proteome in asthma.
References Morgenstern, R., et al.: Biochem. J., 260, 577 (1989), Armstrong, R., et al.: Chem. Res. Toxicol., 10, 2 (1997), Larsen, J., et al.: Ann. Allergy, 71, 103 (1993),

Formula: C₂₆H₂₆ClN₂O₃S₂·Na

Color and Shape: Neat

Molecular weight: 537.07

Ref: TR-M424500

MK 571

CAS: 115104-28-4

MK 571 is a drug that inhibits the ATP-binding cassette (ABC) transporter. MK 571 has been shown to inhibit leukotriene production in hl-60 cells and increase ATP release from myocardial infarcted hearts. It also inhibits the activity of nonsteroidal anti-inflammatory drugs and has been shown to have synergistic effects with other chemotherapeutic agents in cancer treatment.

Formula: C₂₆H₂₇ClN₂O₃S₂

Purity: Min. 95%

Molecular weight: 515.09 g/mol

Ref: 3D-QEA10428