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CAS 115178-97-7

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20-TRIFLUORO LEUKOTRIENE B4

Description:
20-Trifluoro Leukotriene B4 (CAS 115178-97-7) is a synthetic derivative of leukotriene B4, a potent inflammatory mediator involved in various physiological processes, particularly in the immune response. The introduction of trifluoromethyl groups enhances its lipophilicity and stability, potentially affecting its biological activity and interactions with receptors. This compound is characterized by its ability to modulate immune cell functions, including chemotaxis and activation of leukocytes. It may also exhibit altered pharmacokinetics compared to its non-fluorinated counterparts, influencing its therapeutic potential and applications in research. The trifluoromethyl substitution can lead to increased resistance to enzymatic degradation, making it a valuable tool in studying leukotriene pathways and their implications in inflammatory diseases. As with many fluorinated compounds, it is essential to consider its environmental impact and biocompatibility in any practical applications. Overall, 20-Trifluoro Leukotriene B4 serves as an important compound for understanding leukotriene biology and developing potential therapeutic strategies targeting inflammatory conditions.
Formula:C20H29F3O4
InChI:InChI=1/C20H29F3O4/c21-20(22,23)16-9-5-1-2-6-11-17(24)12-7-3-4-8-13-18(25)14-10-15-19(26)27/h2-4,6-8,12-13,17-18,24-25H,1,5,9-11,14-16H2,(H,26,27)/b4-3+,6-2-,12-7+,13-8-/t17-,18-/m1/s1
Synonyms:
  • 5S,12R-Dihydroxy-20,20,20-Trifluoro-6Z,8E,10E,14Z-Eicosatetraenoic Acid
  • (5S,6Z,8E,10E,12R,14Z)-20,20,20-trifluoro-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid
  • 20-trifluoromethyl-leukotriene B4
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