CAS 1152-61-0: Benzyloxycarbonyl-L-aspartic acid
Description:Benzyloxycarbonyl-L-aspartic acid, commonly referred to as Z-Asp, is a derivative of the amino acid aspartic acid, characterized by the presence of a benzyloxycarbonyl (Z) protecting group. This compound is typically used in peptide synthesis as a protecting group for the amino functionality of aspartic acid, which helps prevent unwanted reactions during the synthesis process. The Z group is stable under basic conditions but can be removed under acidic conditions, allowing for selective deprotection. Benzyloxycarbonyl-L-aspartic acid is a white to off-white crystalline solid and is soluble in organic solvents such as methanol and dimethyl sulfoxide (DMSO), but has limited solubility in water. Its molecular structure includes a carboxylic acid functional group, contributing to its acidic properties. The compound is utilized in various biochemical applications, including the synthesis of peptides and proteins, and serves as an important intermediate in the development of pharmaceuticals. Proper handling and storage are essential due to its reactivity and potential for hydrolysis in aqueous environments.
Formula:C12H13NO6
InChI:InChI=1S/C12H13NO6/c14-10(15)6-9(11(16)17)13-12(18)19-7-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,18)(H,14,15)(H,16,17)/t9-/m0/s1
InChI key:InChIKey=XYXYXSKSTZAEJW-VIFPVBQESA-N
SMILES:O=C(O)CC(NC(=O)OCC=1C=CC=CC1)C(=O)O
- Synonyms:
- (2S)-2-(Phenylmethoxycarbonylamino)butanedioic acid
- (2S)-2-[[(Benzyloxy)carbonyl]amino]butanedioic acid
- (2S)-2-{[(benzyloxy)carbonyl]amino}butanedioate
- <span class="text-smallcaps">L</span>-Aspartic acid, N-[(phenylmethoxy)carbonyl]-
- Aspartic acid, N-carboxy-, N-benzyl ester
- Aspartic acid, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
- Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid
- CBZ-L-Aspartic Acid-OH
- Carbobenzoxy-<span class="text-smallcaps">L</span>-aspartic acid
- Cbz-Asp-OH
- See more synonyms
- Cbz-L-aspartic acid
- N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-aspartic acid
- N-Benzyloxycarbonyl-L-aspartic acid
- N-Benzyloxylcarbonyl-<span class="text-smallcaps">L</span>-aspartic acid
- N-CBZ-L-Aspartic acid N-Carbobenzyloxy-L-aspartic acid
- N-Carbobenzoxy-<span class="text-smallcaps">L</span>-aspartic acid
- N-Carbobenzoxy-L-aspatic acid
- N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-aspartic acid
- N-Cbz-L-Asp-OH
- N-Cbz-L-aspartic acid
- N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-aspartic acid
- N-[(benzyloxy)carbonyl]-D-aspartic acid
- N-[(benzyloxy)carbonyl]-L-aspartic acid
- N-[(benzyloxy)carbonyl]aspartic acid
- N-cbz-L-aspartic acid crystalline
- NALPHA-Benzyloxycarbonyl-L-aspartic acid
- NSC 88479
- NSC 9972
- Z-Asp-OH
- Z-L-Aspartic acid
- z-Asp
- Carbobenzoxy-L-aspartic acid
- N-[(Phenylmethoxy)carbonyl]-L-aspartic acid
- Aspartic acid, N-carboxy-, N-benzyl ester, L-
- L-Aspartic acid, N-[(phenylmethoxy)carbonyl]-