CAS: 1152311-62-0 - 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide

Formula: C₂₆H₂₇F₃N₂O₆

InChI: InChI=1S/C26H27F3N2O6/c1-24(2,13-33)22-8-14-7-18(17(27)10-19(14)31(22)11-16(34)12-32)30-23(35)25(5-6-25)15-3-4-20-21(9-15)37-26(28,29)36-20/h3-4,7-10,16,32-34H,5-6,11-13H2,1-2H3,(H,30,35)/t16-/m1/s1

InChI key: InChIKey=MJUVRTYWUMPBTR-MRXNPFEDSA-N

SMILES: O=C(NC1=CC=2C=C(N(C2C=C1F)CC(O)CO)C(C)(C)CO)C3(C4=CC=C5OC(F)(F)OC5=C4)CC3

Synonyms:

• (R)-1-(2,2-Difluorobenzo[D] [1,3]Dioxol-5-Yl)-N-(1-(2,3-Dihydroxypropyl)-6-Fluoro-2-(1-Hydroxy-2-Methylpropan-2-Yl)-1H-Indol-5-Yl) Cyclopropanecarboxamide
• 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide
• 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-{1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methyl-2-propanyl)-1H-indol-5-yl}cyclopropanecarboxamide
• Cs-1078
• Cyclopropanecarboxamide, 1-(2,2-Difluoro-1,3-Benzodioxol-5-Yl)-N-[1-[(2R)-2,3-Dihydroxypropyl]-6-Fluoro-2-(2-Hydroxy-1,1-Dimethylethyl)-1H-Indol-5-Yl]-
• Tezacaftor
• VX 661

Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-

CAS: 1152311-62-0

• Formula: C₂₆H₂₇F₃N₂O₆
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 520.4976

Tezacaftor (VX-661)

CAS: 1152311-62-0

• Formula: C₂₆H₂₇F₃N₂O₆
• Molecular weight: 520.51

Tezacaftor-d4 (VX-661-d4)

CAS: 1152311-62-01961280-24-9

• Formula: C₂₆H₂₃D₄F₃N₂O₆
• Molecular weight: 524.207

Tezacaftor

CAS: 1152311-62-0

• Color and Shape: Neat

Tezacaftor

CAS: 1152311-62-0

Tezacaftor (VX661) is a small molecule that can be used as a corrector of the …

• Formula: C₂₆H₂₇F₃N₂O₆
• Purity: 100% - 99.69%
• Color and Shape: Solid
• Molecular weight: 520.5

Tezacaftor

CAS: 1152311-62-0

Applications Tezacaftor is used as a combination therapy with Ivacaftor for the treatment of patients …

• Formula: C₂₆H₂₇F₃N₂O₆
• Color and Shape: White To Light Yellow
• Molecular weight: 520.5

Tezacaftor-D4

CAS: 1152311-62-0

• Formula: C₂₆D₄H₂₃F₃N₂O₆
• Color and Shape: Neat
• Molecular weight: 524.52

Tezacaftor

CAS: 1152311-62-0

Potentiates cystic fibrosis transmembrane conductance regulator (CFTR)

• Formula: C₂₆H₂₇F₃N₂O₆
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 520.5 g/mol