CAS 115250-39-0

Tetrabenzyl-voglibose

Description:

Tetrabenzyl-voglibose is a synthetic compound primarily known for its application in the treatment of diabetes, particularly as an alpha-glucosidase inhibitor. This substance is a derivative of voglibose, which is a naturally occurring carbohydrate that helps to regulate blood sugar levels by slowing down the digestion of carbohydrates in the intestines. Tetrabenzyl-voglibose is characterized by its complex molecular structure, which includes multiple benzyl groups that enhance its lipophilicity and potentially its pharmacokinetic properties. The compound is typically administered orally and is designed to reduce postprandial hyperglycemia by delaying carbohydrate absorption. Its efficacy and safety profile are evaluated through clinical studies, and it is important to consider potential side effects, such as gastrointestinal discomfort, which are common with alpha-glucosidase inhibitors. As with any pharmaceutical agent, its use should be guided by healthcare professionals, taking into account individual patient needs and conditions.

Formula: C₃₈H₄₅NO₇

InChI: InChI=1/C38H45NO7/c40-22-33(23-41)39-34-21-38(42,28-43-24-29-13-5-1-6-14-29)37(46-27-32-19-11-4-12-20-32)36(45-26-31-17-9-3-10-18-31)35(34)44-25-30-15-7-2-8-16-30/h1-20,33-37,39-42H,21-28H2/t34?,35-,36?,37-,38-/m0/s1

SMILES: c1ccc(cc1)COC[C@]1(CC([C@@H](C([C@@H]1OCc1ccccc1)OCc1ccccc1)OCc1ccccc1)NC(CO)CO)O

Synonyms:

• TBV
• 2-({(2S,4S,5S)-2,3,4-tris(benzyloxy)-5-[(benzyloxy)methyl]-5-hydroxycyclohexyl}amino)propane-1,3-diol

D-epi-Inositol, 3,4-dideoxy-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-C-[(phenylmethoxy)methyl]-1,5,6-tris-O-(phenylmethyl)-

CAS: 115250-39-0

Formula: C₃₈H₄₅NO₇

Purity: %

Color and Shape: Solid

Molecular weight: 627.7664

Ref: IN-DA000GI8

2-(((1S,2S,3R,4S,5S)-2,3,4-Tris(benzyloxy)-5-((benzyloxy)methyl)-5-hydroxycyclohexyl)amino)propane-1,3-diol

CAS: 115250-39-0

2-(((1S,2S,3R,4S,5S)-2,3,4-Tris(benzyloxy)-5-((benzyloxy)methyl)-5-hydroxycyclohexyl)amino)propane-1,3-diol

Purity: 95%

Molecular weight: 627.78g/mol

Ref: 54-OR1074731

1,5,6,7-Tetra-O-benzylvoglibose

CAS: 115250-39-0

Ref: 7W-GC9264

Tetrabenzyl Voglibose

CAS: 115250-39-0

Applications Tetrabenzyl-voglibose is a derivative of Voglibose which is an α-Glucosidase inhibitor used as an antidiabetic.
References Matsuo, T., et al.: Am. J. Clin. Nutr., 55, 314S (1992), Goke, B., et al.: Digestion, 56, 493 (1995), Shinozaki, K., et al.: Metabolism, 45, 731 (1996)

Formula: C₃₈H₄₅NO₇

Color and Shape: White

Molecular weight: 627.77

Ref: TR-T289215

1,5,6,7-Tetra-O-benzylvoglibose

CAS: 115250-39-0

1,5,6,7-Tetra-O-benzylvoglibose is a naturally occurring pentose that is classified as an inhibitor of protein synthesis. It has been shown to inhibit the growth of tumor cells and may be useful in the treatment of cancer. 1,5,6,7-Tetra-O-benzylvoglibose binds to cation channels and blocks their activity. This prevents the influx of calcium ions into the cell which is required for cell division. 1,5,6,7-Tetra-O-benzylvoglibose also inhibits tumor metastases by inhibiting proliferation of myeloid derived suppressor cells (MDSCs). 1,5,6,7 Tetra-O-benzylvoglibose has been shown to inhibit growth factor signaling pathways in cardiac tissue and reduce the risk of cardiac disease development.

Formula: C₃₈H₄₅NO₇

Purity: Min. 95%

Molecular weight: 627.77 g/mol

Ref: 3D-MT08762